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Table 1 Patient characteristics according to Berlin and LIS categories of ARDS at baseline

From: Albumin rather than C-reactive protein may be valuable in predicting and monitoring the severity and course of acute respiratory distress syndrome in critically ill patients with or at risk for the syndrome after new onset fever

Berlin category

0

1

2

3

P-value

 

N = 53

N = 9

N = 32

N = 7

 

Age, years

61 (30)

71 (22)

63 (24)

69 (29)

0.21

Sex, male

39 (74)

5 (56)

20 (63)

5 (71)

0.60

SAPS II admission

46 (20)

59 (24)

49 (16)

44 (57)

0.39

SOFA D0

7 (4)

8 (5)

9 (5)

10 (5)

0.06

ICU days until inclusion

6 (12)

7 (19)

8 (12)

9 (32)

0.98

CVP D0, mmHg

9 (5)

5 (2)

6 (6)

7 (3)

0.26

CVP D1, mmHg

8 (5)

6 (5)

7 (4)

6 (0)

0.83

CVP D2, mmHg

7 (4)

9 (2)

6 (4)

5 (0)

0.25

CVP D7, mmHg

7 (4)

9 (4)

7 (5)

9 (1)

0.49

Vasopressor use D0-7

28 (53)

6 (67)

23 (72)

5 (71)

0.20

Renal replacement therapy D0-7

3 (6)

1 (11)

4 (13)

0

0.57

Albumin 20% administration (100 mL) D0-7

3 (6)

2 (22)

8 (25)

0

0.03

Corticosteroids use D -7-0

23 (43)

5 (56)

14 (44)

3 (43)

0.92

Corticosteroid use D 0-7

23 (43)

7 (78)

16 (50)

4 (57)

0.28

28-day mortality

9 (17)

4 (44)

10 (31)

3 (43)

0.15

LIS category

LIS <1

LIS 1.0-2.5

LIS >2.5

  
 

N =14

N = 69

N =18

P-value

 

Age, years

62 (28)

63 (24)

59 (28)

0.92

 

Sex, man

10 (71)

47 (68)

12 (67)

0.96

 

SAPS II at admission

49 (20)

47 (20)

45 (23)

0.35

 

SOFA D0

5 (2)

8 (5)

10 (3)

0.004

 

ICU days until inclusion

6 (14)

7 (9)

6 (12)

0.85

 

CVP D0, mmHg

8 (6)

7 (5)

8 (5)

0.79

 

CVP D1, mmHg

7 (4)

7 (6)

7 (4)

0.50

 

CVP D2, mmHg

3 (0)

7 (3)

7 (6)

0.32

 

CVP D7, mmHg

6 (7)

7 (5)

8 (3)

0.61

 

Vasopressor use D0-7

5 (39)

4 (63)

14 (82)

0.05

 

Renal replacement therapy D0-7

0

7 (10)

1 (6)

0.40

 

Albumin 20% administration (100 mL) D 0-7

0

12 (17)

1 (6)

0.12

 

Corticosteroids use D -7-0

6 (43)

31 (45)

8 (44)

0.99

 

Corticosteroid use D 0-7

4 (29)

35 (51)

11 (61)

0.18

 

28-day mortality

2 (14)

18 (26)

6 (33)

0.47

 
  1. Median (interquartile range) or number (percentage), where appropriate. Abbreviations: ARDS- acute respiratory distress syndrome; CPR- cardiopulmonary resuscitation; CVP-central venous pressure; D-day; ICU-intensive care unit; PaO2/FIO2-arterial O2 pressure over inspiratory O2 fraction; PEEP-positive end-expiratory pressure; SAPS-simplified acute physiology score; SOFA-sequential organ failure assessment.