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Table 4 Association between exposure to IQR increase of microbial agent concentration in mattress dust and selected home and personal characteristics with the asthma score and lung function parameters FEV 1 and FVC (mL)

From: Predictors of microbial agents in dust and respiratory health in the Ecrhs

  

Asthma score*aMR (95% CI)

FEV1$aß (95% CI)

FVC$aß (95% CI)

Microbial Agents per IQR

C. herbarum DNA

0.92 (0.78-1.09)

20 (-30; 80)

20 (-50; 80)

Pen. /Asp./Paec. Variotii DNA

1.07 (0.94-1.21)

-10 (-50; 30)

10 (-30; 60)

(1,3)-ß-D-glucan

0.94 (0.81-1.10)

-10 (-100-50)

-40 (-110;30)

Mycobacterium spp. DNA

1.08 (0.93-1.26)

10 (-40; 50)

-20 (-80; 30)

Muramic acid

1.37 (1.17-1.61)

3 (-50; 50)

0.3 (-60; 60)

Gram-positive bacteria DNA

1.07 (0.94-1.21)

-4 (-40;30)

-20 (-60; 30)

Gram-negative bacteria DNA

1.04 (0.91-1.20)

-10 (-50; 30)

-20 (-70; 30)

Dampness and Mould

Damp patches in the bedroom

1.40 (0.97-2.01)

-120 (-240; 2)

-120 (-240; 2)

Visible mould in the bedroom

1.32 (0.84-2.07)

-100 (-240; 40)

-140 (-280; -3)

Condensation on bedroom windows

1.22 (0.96-1.57)

-90 (-160; -10)

-70 (-170; 20)

Dampness at home past 12 months

1.24 (0.97-1.59)

4 (-80; 90)

50 (-50; 150)

Mould at home

   

Current

1.41 (1.07-1.85)

-10 (-100; 80)

60 (-50; 170)

Ever

1.12 (0.75-1.66)

-70 (-190; 50)

-60 (-200; 80)

Water damage

   

Current

1.10 (0.77-1.56)

-10 (-120; 90)

-10 (-140; 120)

Ever

1.16 (0.90-1.51)

-10 (-90; 70)

-20 (-120; 80)

Home / Personal

Cat in the home

1.04 (0.66-1.66)

140 (10; 280)

160 (-10; 320)

Cat in bedroom

0.93 (0.68-1.27)

-3 (-100; 90)

-10 (-130; 100)

Dog at home

1.12 (0.76-1.63)

-10(-130; 100)

-60 (-200; 80)

Dog in bedroom

1.05 (0.72-1.53)

50 (-60; 160)

40 (-100; 180)

Current smoking

1.85 (1.44-2.36)

-70 (-140; 1)

0.1 (-90; 90)

Bed in living room

1.63 (1.10-2.42)

-230 (-390; -80)

-210 (-410; -10)

  1. Results are displayed as adjusted Mean Ratios (aMR) and adjusted ß (aß) with 95% confidence intervals (95% CI), respectively.
  2. *Model asthma score adjusted for: sex, damp patches in the bedroom, condensation on bedroom windows, bed is in living room, current smoking, and season of dust sampling.$Model lung function adjusted for: sex, education, height, weight, damp patches in the bedroom, current water damage in the building, bed is in living room, current smoking and season of dust sampling. Numbers in bold indicate significant associations.