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Table 3 Comparison of HRCT findings between PR3-ANCA positive cases and MPO-ANCA positive cases

From: Comparative investigation of respiratory tract involvement in granulomatosis with polyangiitis between PR3-ANCA positive and MPO-ANCA positive cases: a retrospective cohort study

 

PR3-ANCA

MPO-ANCA

P value

(N = 9)

(N = 6)

Small nodule (<10 mm)

   

 Patients (%)

7 (78 %)

5 (83 %)

1.00

 Unilateral/Bilateral

2/5

0/5

0.470

 Number per person

2.0 (1.5–8.0)

6.0 (5.0–14)

0.142

 Cavity

1

1

NA

Large nodule (≥10, <30 mm)

   

 Patients (%)

3 (33 %)

6 (100 %)

0.0280

 Unilateral/Bilateral

0/3

0/6

NA

 Number per person

4.0 (3.5–4.5)

3.0 (2.0–4.8)

0.596

 Cavity

2

3

NA

Mass (≥30 mm)

   

 Patients (%)

0

1 (17 %)

0.400

 Unilateral/Bilateral

0/0

0/1

NA

 Number per person

0

3.0

NA

 Cavity

0

2

NA

Consolidation

   

 Patients (%)

5 (56 %)

1 (17 %)

0.287

 Unilateral/Bilateral

2/3

1/0

1.00

Ground glass opacity (%)

2 (22 %)

4 (67 %)

0.136

Centrilobular nodular shadow (%)

2 (22 %)

0

0.486

Bronchial wall thickening

5 (56 %)

4 (67 %)

1.00

 Trachea (%)

1 (11 %)

0

1.00

 Main bronchi (%)

2 (22 %)

2 (33 %)

1.00

 lobar bronchi (%)

4 (44 %)

3 (50 %)

1.00

 Segmental bronchi (%)

2 (22 %)

4 (67 %)

0.136

Thickening of interlobular septa (%)

0

2 (33 %)

0.143

Mediastinal/hilar lymphadenopathy (%)

3 (33 %)

3 (50 %)

0.622

Pleural effusion (%)

1 (11 %)

2 (33 %)

0.525

  1. Categorical data are presented as number (percentage), and were analyzed by Fisher’s exact test