Table 2 Absolute values of the morphometric analysis for remodeling markers in the airway and lung tissue

BIOMARKERS

SAL (n = 8)

OVA (n = 8)

OVA-RHO (n = 8)

OVA-C (n = 8)

ORC (n = 8)

Collagen Fibers

9.13 ± 0.36

25.54 ± 1.95 ***

15.95 ± 0.94 *

19.60 ± 1.89 *

10.31 ± 0.97 * / **

Elastic Fibers

2.26 ± 0.43

17.68 ± 2.47 ***

4.53 ± 0.59 *

9.33 ± 0.67 *

4.87 ± 0.52 *

Actin

6.94 ± 0.67

25.59 ± 2.26 ***

12.16 ± 1.25 *

19.97 ± 0.94 *

15.30 ± 1.23 *

TGF-β

4.48 ± 0.53

13.47 ± 1.74 ***

5.35 ± 1.78 *

7.73 ± 1.58 *

5.67 ± 0.91 *

MMP-9

12.35 ± 0.78

26.48 ± 1.48 ***

11.29 ± 1.38 ⁺

13.36 ± 0.49 ⁺

10.82 ± 1.34 ⁺

TIMP-1

4.63 ± 1.25

17.17 ± 1.36 ***

8.13 ± 0.73 *

9.82 ± 1.27 *

7.30 ± 0.98 *

LUNG TISSUE

BIOMARKERS

SAL (n = 8)

OVA (n = 8)

OVA-RHO (n = 8)

OVA-C (n = 8)

ORC (n = 8)

Collagen Fibers

8.62 ± 0.28

22.42 ± 0.68 ***

9.74 ± 0.64 *

13.76 ± 0.32 *

12.35 ± 1.73 *

Elastic Fibers

7.74 ± 0.69

19.49 ± 0.52 ***

12.93 ± 1.37 *

12.85 ± 0.51 *

8.05 ± 1.59 *

Actin

4.52 ± 0.98

13.24 ± 0.74 ***

4.65 ± 0.85 *

4.86 ± 0.84 *

4.94 ± 0.90 *

TGF-β

5.90 ± 0.63

15.24 ± 0.36 ***

6.37 ± 0.69 *

6.46 ± 1.13 *

5.69 ± 0.74 *

MMP-9

12.53 ± 0.95

27.17 ± 0.35 ***

14.53 ± 0.55 ⁺

14.92 ± 0.81 ⁺

13.55 ± 0.56 ⁺

TIMP-1

3.95 ± 0.74

17.19 ± 1.12 ***

12.58 ± 0.59 *

12.18 ± 1.27 *

8.32 ± 1.12 * / **