Table 1 Demographics, clinical-radiological data and bronchoscopic results of malignant and benign peripheral lung lesions
From: Radial endobronchial ultrasound in diagnosing peripheral lung lesions in a high tuberculosis setting
Malignant | Benign | p-value | |||
|---|---|---|---|---|---|
Demographics | |||||
Subjects (n) | 76 | 44 | |||
Age | 65.1 ± 10.3 | 58.2 ± 15.0 | 0.004 | ||
Male gender (%) | 60.5 | 70.5 | 0.326 | ||
Smoking (%) | 44.6 | 33.3 | 0.247 | ||
Diabetes mellitus (%) | 21.6 | 14.3 | 0.461 | ||
Presenting symptoms (n) | |||||
Cough | 27 | 14 | 0.841 | ||
Dyspnoea | 14 | 1 | 0.037 | ||
Weight Loss | 12 | 4 | 0.440 | ||
Hemoptysis | 5 | 4 | 0.721 | ||
Fever | 2 | 5 | 0.097 | ||
Asymptomatic | 23 | 16 | 0.442 | ||
Size | |||||
Mean (mm) | 26 ± 12 | 24 ± 13 | 0.357 | ||
≤20 mm | 28 (36.0) | 21 (47.7) | |||
>20 mm | 48 (64.0) | 23 (52.3) | |||
Common radiologic characteristics | |||||
Spiculation/Lobulation | 44 (57.9) | 10 (23.8) | <0.001 | ||
Cavitation | 4 (5.3) | 13 (31.0) | <0.001 | ||
Ground gass/Semisolid | 4 (5.3) | 3 (7.1) | 0.698 | ||
Appearance | |||||
Tree-in-bud changes | 1 (1.3) | 6 (13.6) | 0.009 | ||
Distance of lesion from pleura (mm) | 17 ± 13 | 16 ± 14 | 0.606 | ||
Lobar Position (n) | 0.582 | ||||
Right upper lobe | 20 | 12 | |||
Right middle lobe | 6 | 5 | |||
Right lower lobe | 20 | 8 | |||
Left upper lobe | 28 | 14 | |||
Left lower lobe | 2 | 5 | |||
Final diagnosis | |||||
Non-small cell lung cancer | 63 (82.9) | Pulmonary tuberculosis | 22 (50.0) | ||
Pneumonia | 15 (34.1) | ||||
Small cell lung cancer | 2 (2.6) | Other diagnoses | |||
Pulmonary metastases | 10 (13.2) | Organising pneumonia | 5 (11.4) | ||
Bronchial carcinoid | 1 (1.3) | Scarring | 2 (4.6) | ||
Cases diagnosed by radial EBUS | Non-small cell lung cancer | 45 (59.2) | Pulmonary tuberculosis | 17 (38.6) | |
Pneumonia | 12 (27.3) | ||||
Small cell lung cancer | 2 (2.6) | Other diagnoses | |||
Pulmonary metastases | 2 (2.6) | Organising pneumonia | 2 (4.5) | ||
Bronchial carcinoid | 1 (1.3) | Scarring | 2 (4.5) | ||
Yield based on known location of probe | |||||
Within lesion | 49 (71.6) | 29 (78.9) | |||
Adjacent to lesion | 16 (23.9) | 6 (15.8) | |||
Outside lesion | 3 (4.5) | 2 (5.3) | |||