| Nonsmokers | Healthy smokers | COPD |  |
---|---|---|---|---|
n = 6 | n = 11 | n = 8 | p | |
Age (years) | 47.60 ± 11.82 | 49.58 ± 5.57 | 57.0 ± 4.66 | 0.052 |
Gender (male, n (%)) | 4 (66.7) | 4 (36.3) | 5 (62.5) | 0.327 |
BMI (kg/m2) | 31.13 ± 5.26 | 30.78 ± 4.74 | 29.30 ± 5.88 | 0.743 |
Racea (White, n (%)) | 3 (50.0) | 2 (18.2) | 0 (0) | 0.035 |
FEV1 ( % pred) | 89.50 ± 20.52* | 101.17 ± 16.30* | 46.25 ± 8.83 | <0.0001 |
FVC ( % pred) | 92.90 ± 16.23 | 103.67 ± 16.87* | 74.13 ± 12.70 | 0.001 |
FEV1/FVC | 88.2 ± 21.70* | 96.67 ± 6.14* | 52.38 ± 11.95 | <0.0001 |
Smoking History (pack years) | 0* ** | 25.58 ± 10.66 | 22.25 ± 9.00 | <0.0001 |
Current Smoking (n, %) | 0 (0) | 11 (100) | 5 (62.5) | <0.0001 |
Chronic Bronchitis (n, %) | 0 (0) | 2 (18.2) | 5 (62.5) | 0.006 |
MVD (μL/mm2) | 3.42 ± 3.07** | 27.78 ± 10.24 | 16.82 ± 16.29 | 0.002 |