|  | Nonsmokers (n = 6) | Healthy smokers (n = 11) | COPD (n = 8) | P |
---|---|---|---|---|---|
Chemokines | Eotaxin | 83.92 ± 57.41 | 96.16 ± 58.86 | 96.42 ± 75.40 | 0.920 |
CXCL8 | 1.20 ± 21.92* | 11.05 ± 8.92 | 6.01 ± 5.90 | 0.028 | |
IP10 | 233.94 ± 125.07 | 671.55 ± 544.81 | 670.36 ± 751.53 | 0.287 | |
CCL2 | 200.98 ± 128.03 | 310.63 ± 149.19 | 207.02 ± 76.06 | 0.106 | |
CCL7 | 17.33 ± 17.44** | 40.66 ± 22.34 | 50.74 ± 25.88 | 0.031 | |
CCL22 | 714.23 ± 524.71* | 1335.51 ± 486.74** | 750.37 ± 251.39 | 0.009 | |
CCL3 | 17.44 ± 25.47 | 7.88 ± 21.72 | 8.33 ± 3.55 | 0.255 | |
CCL4 | 9.69 ± 10.50* | 42.04 ± 24.48 | 25.98 ± 15.60 | 0.009 | |
Th1 | IFNγ | 4.21 ± 2.63 | 9.58 ± 6.13 | 19.24 ± 28.76 | 0.253 |
IL12p40 | Undetectable | 38.97 ± 8.01** | 20.44 ± 17.22 | 0.035 | |
Th2 | IL4 | 10.71 ± 13.20 | 15.35 ± 12.26 | 47.77 ± 81.07 | 0.256 |
IL9 | 1.16 ± 1.83 | 1.71 ± 1.44 | 2.66 ± 2.95 | 0.389 | |
Th17 | GCSF | 83.92 ± 57.41 | 74.14 ± 81.80 | 25.79 ± 25.96 | 0.059 |
IL6 | 11.39 ± 2.58 | 9.46 ± 2.46 | 64.27 ± 163.01 | 0.410 | |
IL17 | Undetectable | 8.76 ± 0.87 | 8.62 ± 1.03 | 0.809 | |
Other | EGF | 12.65 ± 3.31 | 13.96 ± 8.19 | 19.16 ± 19.66 | 0.559 |
IFNα2 | 17.19 ± 11.28 | 57.43 ± 37.42 | 67.87 ± 71.16 | 0.155 | |
IL1β | 2.86 ± 4.44 | 1.97 ± 2.59 | 5.30 ± 7.01 | 0.323 | |
IL10 | 9.35 ± 7.73 | 6.78 ± 6.08 | 16.11 ± 27.39 | 0.478 | |
IL15 | 5.18 ± 3.52 | 5.53 ± 3.20 | 5.75 ± 5.19 | 0.965 | |
TGFα | Undetectable | Undetectable | Undetectable |  | |
VEGF | 130.03 ± 100.23 | 195.44 ± 55.90 | 258.95 ± 295.52 | 0.427 |