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Table 3 Plasma chemokines

From: Plasma Chemokine signature correlates with lung goblet cell hyperplasia in smokers with and without chronic obstructive pulmonary disease

  

Nonsmokers (n = 6)

Healthy smokers (n = 11)

COPD (n = 8)

P

Chemokines

Eotaxin

83.92 ± 57.41

96.16 ± 58.86

96.42 ± 75.40

0.920

CXCL8

1.20 ± 21.92*

11.05 ± 8.92

6.01 ± 5.90

0.028

IP10

233.94 ± 125.07

671.55 ± 544.81

670.36 ± 751.53

0.287

CCL2

200.98 ± 128.03

310.63 ± 149.19

207.02 ± 76.06

0.106

CCL7

17.33 ± 17.44**

40.66 ± 22.34

50.74 ± 25.88

0.031

CCL22

714.23 ± 524.71*

1335.51 ± 486.74**

750.37 ± 251.39

0.009

CCL3

17.44 ± 25.47

7.88 ± 21.72

8.33 ± 3.55

0.255

CCL4

9.69 ± 10.50*

42.04 ± 24.48

25.98 ± 15.60

0.009

Th1

IFNγ

4.21 ± 2.63

9.58 ± 6.13

19.24 ± 28.76

0.253

IL12p40

Undetectable

38.97 ± 8.01**

20.44 ± 17.22

0.035

Th2

IL4

10.71 ± 13.20

15.35 ± 12.26

47.77 ± 81.07

0.256

IL9

1.16 ± 1.83

1.71 ± 1.44

2.66 ± 2.95

0.389

Th17

GCSF

83.92 ± 57.41

74.14 ± 81.80

25.79 ± 25.96

0.059

IL6

11.39 ± 2.58

9.46 ± 2.46

64.27 ± 163.01

0.410

IL17

Undetectable

8.76 ± 0.87

8.62 ± 1.03

0.809

Other

EGF

12.65 ± 3.31

13.96 ± 8.19

19.16 ± 19.66

0.559

IFNα2

17.19 ± 11.28

57.43 ± 37.42

67.87 ± 71.16

0.155

IL1β

2.86 ± 4.44

1.97 ± 2.59

5.30 ± 7.01

0.323

IL10

9.35 ± 7.73

6.78 ± 6.08

16.11 ± 27.39

0.478

IL15

5.18 ± 3.52

5.53 ± 3.20

5.75 ± 5.19

0.965

TGFα

Undetectable

Undetectable

Undetectable

 

VEGF

130.03 ± 100.23

195.44 ± 55.90

258.95 ± 295.52

0.427

  1. *p <0.05 vs. healthy smokers, **p <0.05 vs. COPD