From: Haemophilus influenzae induces steroid-resistant inflammatory responses in COPD
Characteristic | COPD | Smokers | Non-smokers |
---|---|---|---|
(n = 7) | (n = 5) | (n = 6) | |
Age | 55.0 ± 4.4 | 59.4 ± 11.6 | 56.8 ± 16.1 |
Gender (M/F) | 6/1 | 4/1 | 5/1 |
Smoking history | |||
Smoking index | 69.3 ± 16.8 | 42.5 ± 3.5 | 0 |
Current/former smoker | 5/2 | 4/1 | 0 |
FEV1/FVC (%) | 60.7 ± 7.9 | 84 ± 8 | 83.6 ± 3.6 |
FEV1 (L) | 2.5 ± 0.4 | 2.9 ± 0.7 | 3.6 ± 1.0 |
FEV1% predicted | 78.3 ± 16.0 | 96 ± 16.3 | 107.2 ± 17.5 |
BAL: | |||
Volume of BAL recovered (ml) | 37.9 ± 10.7 | 51 ± 18.2 | 62 ± 20.8 |
Total cells (cells/μl) | 167 ± 54.9 | 233.5 ± 116 | 210 ± 29.7 |
Differential cell count: | |||
Macrophages (cells/μl) | 21.68 ± 6.46 | 72.39 ± 11,61 | 75,94 ± 2,35 22,07 ± 3.02 |
Lymphocytes (cells/μl) | 31.93 ± 5,29 | 17.9 ± 7,29 | |
Neutrophils (cells/μl) | 45,93 ± 8,59 | 9,69 ± 4,5 | 1,92 ± 0,71 |