Table 1 Baseline characteristics by FVC% change group
By lung-function change category (based on relative change in FVC%)a | ||||||
|---|---|---|---|---|---|---|
Stable [A] | Marginal [B] | Significant [C] | P-value* | |||
(N = 250) | (N = 98) | (N = 142) | [C] vs. [A] | [C] vs. [B] | [B] vs. [A] | |
Male, N (%) | 167 (66.8 %) | 70 (71.4 %) | 98 (69.0 %) | 0.999 | 0.999 | 0.999 |
Age (years), mean (SD) | 60.8 (10.8) | 62.1 (9.6) | 60.9 (11.5) | 0.999 | 0.999 | 0.930 |
BMI, mean (SD) | 26.7 (4.9) | 26.5 (4.4) | 26.3 (4.6) | 0.999 | 0.999 | 0.999 |
Race, N (%)b | ||||||
White | 183 (73.2 %) | 82 (83.7 %) | 104 (73.2 %) | 0.999 | 0.193 | 0.098 |
Black or African American | 34 (13.6 %) | 11 (11.2 %) | 24 (16.9 %) | 0.999 | 0.650 | 0.999 |
Hispanic, Latino, or Spanish Origin | 26 (10.4 %) | 5 (5.1 %) | 13 (9.2 %) | 0.999 | 0.646 | 0.295 |
Asian | 7 (2.8 %) | 1 (1.0 %) | 1 (0.7 %) | 0.479 | 0.999 | 0.952 |
Other | 2 (0.8 %) | 0 (0.0 %) | 0 (0.0 %) | |||
Insurance type, N (%)b | ||||||
Commercial/private insurance | 113 (45.2 %) | 45 (45.9 %) | 80 (56.3 %) | 0.193 | 0.502 | 0.999 |
Medicare | 109 (43.6 %) | 44 (44.9 %) | 61 (43.0 %) | 0.999 | 0.999 | 0.999 |
Medicaid | 26 (10.4 %) | 12 (12.2 %) | 17 (12.0 %) | 0.999 | 0.999 | 0.999 |
Military insurance (VA or active military) | 9 (3.6 %) | 2 (2.0 %) | 3 (2.1 %) | 0.999 | 0.999 | 0.999 |
Other | 0 (0.0 %) | 1 (1.0 %) | 0 (0.0 %) | - | - | - |
No insurance | 8 (3.2 %) | 1 (1.0 %) | 1 (0.7 %) | 0.228 | 0.999 | 0.584 |
Smoking status at diagnosis, N (%) | 0.789 | 0.999 | 0.999 | |||
Never smoked | 98 (39.2 %) | 44 (44.9 %) | 48 (33.8 %) | |||
Former smoker | 124 (49.6 %) | 42 (42.9 %) | 77 (54.2 %) | |||
Current smoker | 21 (8.4 %) | 11 (11.2 %) | 16 (11.3 %) | |||
Unknown/not sure | 7 (2.8 %) | 1 (1.0 %) | 1 (0.7 %) | |||
Exposure to activities/ environmental agents, N (%)b | ||||||
Asbestos | 10 (4.0 %) | 3 (3.1 %) | 11 (7.7 %) | 0.336 | 0.650 | 0.999 |
Farming/agriculture | 27 (10.8 %) | 9 (9.2 %) | 25 (17.6 %) | 0.213 | 0.131 | 0.999 |
Hairdressing | 12 (4.8 %) | 4 (4.1 %) | 4 (2.8 %) | 0.999 | 0.999 | 0.999 |
Metal dust | 18 (7.2 %) | 2 (2.0 %) | 10 (7.0 %) | 0.999 | 0.172 | 0.154 |
Stone cutting/polishing | 7 (2.8 %) | 0 (0.0 %) | 6 (4.2 %) | 0.999 | <0.001* | <0.001* |
Coal mining | 5 (2.0 %) | 1 (1.0 %) | 2 (1.4 %) | 0.999 | 0.999 | 0.999 |
Other | 3 (1.2 %) | 3 (3.1 %) | 2 (1.4 %) | 0.999 | 0.999 | 0.669 |
None | 182 (72.8 %) | 78 (79.6 %) | 92 (64.8 %) | 0.340 | 0.037* | 0.598 |
Family history of pulmonary fibrosis, N (%) | 16 (6.4 %) | 6 (6.1 %) | 5 (3.5 %) | 0.564 | 0.923 | 0.999 |
Measurement period (days) | ||||||
Concurrent, mean (SD) | 172.8 (55.5) | 174.9 (53.7) | 181.6 (56.8) | 0.575 | 0.999 | 0.999 |
Subsequent, mean (SD) | 438.3 (283.1) | 423.0 (280.0) | 340.1 (275.9) | 0.013* | 0.118 | 0.999 |
Total follow-up, mean (SD) | 611.1 (282.7) | 597.9 (285.8) | 521.7 (286.6) | 0.036* | 0.225 | 0.999 |