| |
12-Month IR per Patient
|
IRR
|
|
Rate of IPF-related outpatient visits
|
2.24
|
2.57
|
2.55
|
1.14 (0.89–1.46)
|
0.99 (0.76–1.30)
|
1.15 (0.91–1.45)
|
|
Unscheduled and/or urgent care
|
0.18
|
0.38
|
0.54
|
3.01 (1.51–5.97)
|
1.41 (0.78–2.55)
|
2.13 (1.05–4.34)
|
|
For a suspected AEx
|
0.19
|
0.33
|
0.54
|
2.81 (1.47–5.40)
|
1.64 (0.86–3.11)
|
1.72 (0.80–3.69)
|
|
Rate of outpatient visits indicating that the following medications/treatments were prescribed for IPF
|
|
Prednisone
|
1.06
|
1.16
|
1.60
|
1.51 (1.08–2.10)
|
1.38 (1.02–1.86)
|
1.10 (0.79–1.52)
|
|
Azathioprine
|
0.36
|
0.31
|
0.54
|
1.51 (0.78–2.93)
|
1.72 (0.84–3.53)
|
0.88 (0.44–1.76)
|
|
N-acetylcysteine
|
0.65
|
0.70
|
0.79
|
1.22 (0.79–1.89)
|
1.13 (0.67–1.90)
|
1.08 (0.69–1.70)
|
|
Rate of outpatient visits that included the following tests/procedures
|
|
Arterial blood gas test
|
0.17
|
0.23
|
0.34
|
2.04 (0.77–5.38)
|
1.46 (0.53–4.03)
|
1.40 (0.55–3.56)
|
|
HRCT
|
0.23
|
0.35
|
0.35
|
1.55 (0.74–3.21)
|
1.02 (0.45–2.31)
|
1.51 (0.76–2.99)
|
|
Chest X-ray
|
0.48
|
0.66
|
0.60
|
1.23 (0.75–2.02)
|
0.90 (0.55–1.48)
|
1.36 (0.84–2.20)
|
|
Lung biopsy
|
0.03
|
0.04
|
0.01
|
0.44 (0.02–8.70)
|
0.31 (0.02–4.91)
|
1.42 (0.13–15.70)
|
|
Pulmonary rehabilitation
|
0.18
|
0.19
|
0.26
|
1.44 (0.79–2.63)
|
1.35 (0.58–3.11)
|
1.07 (0.52–2.23)
|
|
Rate of IFP-related ER visits
|
0.35
|
0.54
|
0.53
|
1.53 (0.71–3.28)
|
0.98 (0.51–1.87)
|
1.56 (0.66–3.71)
|
|
For a suspected AEx
|
0.13
|
0.22
|
0.29
|
2.22 (0.95–5.21)
|
1.32 (0.60–2.87)
|
1.69 (0.67–4.27)
|
|
Rate of ER visits that included the following tests/procedures
|
|
Arterial blood gas test
|
0.15
|
0.35
|
0.33
|
2.24 (1.01–4.99)
|
0.95 (0.45–2.00)
|
2.36 (1.01–5.49)
|
|
HRCT
|
0.09
|
0.18
|
0.20
|
2.17 (0.85–5.58)
|
1.09 (0.37–3.22)
|
1.99 (0.60–6.67)
|
|
Chest X-ray
|
0.20
|
0.28
|
0.30
|
1.51 (0.69–3.32)
|
1.10 (0.55–2.21)
|
1.37 (0.61–3.09)
|
|
Supplemental oxygen therapy
|
0.17
|
0.23
|
0.29
|
1.74 (0.73–4.14)
|
1.26 (0.52–3.04)
|
1.39 (0.46–4.20)
|
|
Rate of IPF-related hospitalizations
|
0.24
|
0.32
|
0.61
|
2.53 (0.70–9.10)
|
1.89 (0.94–3.78)
|
1.34 (0.34–5.29)
|
|
For a suspected AEx
|
0.09
|
0.21
|
0.43
|
4.69 (1.84–11.99)
|
2.05 (1.03–4.08)
|
2.29 (0.82–6.35)
|
|
Rate of hospital days
|
1.13
|
2.32
|
5.25
|
4.63 (1.31–16.42)
|
2.27 (0.86–5.97)
|
2.05 (0.66–6.33)
|
|
Rate of ICU stays
|
0.05
|
0.17
|
0.26
|
4.95 (1.20–20.41)
|
1.53 (0.59–3.99)
|
3.23 (0.72–14.53)
|
|
Rate of ICU days
|
0.30
|
0.69
|
1.22
|
4.05 (0.79–20.91)
|
1.75 (0.58–5.35)
|
2.31 (0.54–9.83)
|
|
Rate of hospitalizations that included the following tests/procedures
|
|
Arterial blood gas test
|
0.10
|
0.19
|
0.35
|
3.58 (1.33–9.64)
|
1.87 (0.73–4.80)
|
1.92 (0.61–6.00)
|
|
Mechanical ventilation
|
0.04
|
0.11
|
0.14
|
3.29 (0.63–17.23)
|
1.33 (0.38–4.70)
|
2.47 (0.57–10.73)
|
|
Non-invasive ventilation
|
0.02
|
0.08
|
0.22
|
10.17 (3.25–31.86)
|
2.80 (1.05–7.51)
|
3.63 (0.90–14.70)
|
|
Supplemental oxygen therapy
|
0.07
|
0.13
|
0.28
|
3.95 (1.38–11.29)
|
2.11 (0.93–4.82)
|
1.87 (0.62–5.66)
|
| |
12-Month Risk
|
OR
|
|
Risk of having ≥1 outpatient visit
|
97.5 %
|
97.3 %
|
95.0 %
|
0.48 (0.14–1.62)
|
0.52 (0.12–2.20)
|
0.93 (0.23–3.76)
|
|
Unscheduled or urgent care
|
11.4 %
|
26.9 %
|
34.5 %
|
4.10 (1.95–8.63)
|
1.43 (0.69–2.98)
|
2.87 (1.39–5.92)
|
|
For a suspected AEx
|
12.7 %
|
21.9 %
|
33.8 %
|
3.52 (1.62–7.67)
|
1.82 (0.82–4.05)
|
1.93 (0.90–4.15)
|
|
Risk of having ≥1 ER visit
|
14.4 %
|
29.4 %
|
32.4 %
|
2.85 (1.36–5.98)
|
1.15 (0.53–2.52)
|
2.47 (1.22–5.03)
|
|
For a suspected AEx
|
7.8 %
|
16.7 %
|
22.1 %
|
3.33 (1.40–7.94)
|
1.42 (0.57–3.54)
|
2.35 (0.98–5.65)
|
|
Risk of having ≥1 hospitalizations
|
7.8 %
|
19.1 %
|
30.0 %
|
5.04 (2.13–11.93)
|
1.82 (0.71–4.66)
|
2.76 (1.14–6.70)
|
|
Intensive care unit (ICU) stay
|
2.4 %
|
8.4 %
|
12.4 %
|
5.86 (1.43–24.01)
|
1.56 (0.41–5.90)
|
3.77 (0.88–16.03)
|
|
For a suspected AEx
|
5.9 %
|
15.1 %
|
27.8 %
|
6.08 (2.45–15.07)
|
2.16 (0.84–5.54)
|
2.81 (1.10–7.20)
|
