Fig. 1

Differential levels of miR-21 and miR-26a in plasma from wheezing children. a RT-qPCR results of candidate miRNAs in plasma from 20 LRI control and 20 wheezing + LRI children. b RT-qPCR results of miR-21, miR-25, miR-26a, miR-133a and miR-148 in plasma from 35 indifferent control, 35 LRI control and 70 wheezing + LRI children. c Scattered dot plots of plasma miR-21 and miR-26a in wheezing + LRI children of different ages and genders. Cel-miR-39 was used as internal control for circulating miRNA. Differences among three groups were analyzed by Kruskal-Wallis test followed Mann-Whitney test for difference between groups according to data characteristics. **: p < 0.01, ***: p < 0.001