A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults

BMC Pulmonary Medicine

Table 1 Selected population IPD and CAP disease burden estimates for PCV13 serotype CAP

Study	Population	Year	Incidence/100,000
Waight et al [21]	England and Wales IPD – all ages	2013/14	1.40
Waight et al [21]	England and Wales IPD- age >65 years	2013/14	3.72
Rodrigo et al [29]	Nottingham (multicentre) CAP- adults all ages	2012/13	8.60
Rodrigo et al [29]	Nottingham (multicentre) CAP- Age >65 years	2012/13	16.75
Van Hoek et al [39]	England Risk groups^a Adult	2008/9	37.10^b
Van Hoek et al [39]	England Risk groups^a ≥65 years	2008/9	39.84^b

CAP refers to non-invasive and invasive pneumococcal community acquired pneumonia
^arisk groups include asplenia/splenic dysfunction/chronic respiratory disease/chronic heart disease/chronic kidney disease/chronic liver disease/diabetes/immunosuppression/cochlear implants/cerebrospinal fluid leaks [39]
^bdata extracted based on reported 83 % coverage of total IPD incidence by PCV13 during 2008/9

ISSN: 1471-2466