Table 2 Parameters 1 year post-PEA according to non-residual and residual PH

Patients, n (%)

16 (43.2)

21 (56.8)

WHO functional class, (%)

a

0.002

 I

46.2

None

 II

53.8

57.1

 III

None

42.9

 IV

None

None

6MWT

 6MWD (m)

487.6 ± 72.1

432.4 ± 148.9

0.26

 Rest SpO₂ (%)

97 ± 1.9

94.8 ± 3.1

0.05

 Peak SpO2 (%)

94.3 ± 4.4

90.8 ± 4.1

0.05

 Δ SpO2 (%)

−2.7 ± 3.8

−3.9 ± 4.4

0.47

 Rest HR (beats^amin-1)

83.9 ± 15.1

83.2 ± 13.9

0.9

 Peak HR (beats^amin-1)

101.6 ± 15.2

111.5 ± 17.6

0.2

 Δ HR (beats^amin-1)

17.8 ± 6.3

28.3 ± 14.4

0.06

 HRR (%)

24.3 ± 11.5

28.3 ± 14.4

0.05

 Δ Borg

1.7 ± 1.9

3.9 ± 2.4

0.02

 Supplemental Oxygen (n, %)

1 (6.3)

2 (9.5)

-

Lung function

 FEV1 (% pred.)

93.9 ± 12.8

83.9 ± 10.6

0.02

 FEV1/FVC (% pred.)

95.8 ± 13.9

86.7 ± 9.2

0.03

 TLC (% pred.)

104.2 ± 15.2

105.2 ± 18.3

0.87

 VC (% pred.)

96.8 ± 14.0

92.1 ± 11.6

0.3

RHC

 mPAP (mm Hg)

19.7 ± 3.2

36 ± 7.5

0.001

 RAP (mm Hg)

5.5 ± 2.4

8.7 ± 5.1

0.04

 PVR (dyne^as/cm⁵)

218.3 ± 280.9

415.9 ± 163.7

0.012

 CI (l/min/m²)

2.9 ± 0.4

2.6 ± 0.6

0.09

 PAWP (mm Hg)

8.9 ± 3.8

12.2 ± 4.7

0.037

Echocardiography

 TAPSE (mm)

18.3 ± 2.7

16.7 ± 3.6

0.2

 PASP (mm Hg)

50.6 ± 29.2

59.5 ± 21.9

0.5

CPET^b

 Peak VO₂ (ml/min/kg)

15.2 ± 4.5

13.3 ± 3.9

0.36

 Rest V_D/V_T

30.3 ± 5.1

35.3 ± 6.4

0.35

 Peak V_D/V_T

27.7 ± 6.1

41.2 ± 12.1

0.13

 Rest V_D, L

0.22 ± 0.07

0.37 ± 0.09

0.09

 Peak V_D, L

0.63 ± 0.1

0.78 ± 0.26

0.39

 Rest SpO₂ (%)

95.1 ± 1.3

93.7 ± 1.8

0.10

 Peak SpO2 (%)

89.1 ± 7.3

89.6 ± 4.6

0.86

 Δ SpO2 (%)

−5.2 ± 5.4

−3.6 ± 3.3

0.69

 Rest HR (beats^amin-1)

76.1 ± 12.4

69.9 ± 11.7

0.15

 Peak HR (beats^amin-1)

125.3 ± 22.4

116.6 ± 19.9

0.25

 Δ HR (beats^amin-1)

49.2 ± 19.3

46.7 ± 19.9

0.72

 HRR (%)

55.1 ± 21.1

54.3 ± 21.8

0.92

Jamieson-Type, (%)

a

0.15

 I

14.2

46.7

 II

42.9

20

 III

42.9

33.3

Laboratory

 NT-proBNP (pg/ml)

175.0 [56–259]

389.0 [95–703]

0.18