Skip to main content

Advertisement

Table 2 Parameters 1 year post-PEA according to non-residual and residual PH

From: Heart rate response during 6-minute walking testing predicts outcome in operable chronic thromboembolic pulmonary hypertension

  Non-residual PH Residual PH p-value
Patients, n (%) 16 (43.2) 21 (56.8)  
WHO functional class, (%)   a 0.002
 I 46.2 None  
 II 53.8 57.1  
 III None 42.9  
 IV None None  
6MWT    
 6MWD (m) 487.6 ± 72.1 432.4 ± 148.9 0.26
 Rest SpO2 (%) 97 ± 1.9 94.8 ± 3.1 0.05
 Peak SpO2 (%) 94.3 ± 4.4 90.8 ± 4.1 0.05
 Δ SpO2 (%) −2.7 ± 3.8 −3.9 ± 4.4 0.47
 Rest HR (beatsamin-1) 83.9 ± 15.1 83.2 ± 13.9 0.9
 Peak HR (beatsamin-1) 101.6 ± 15.2 111.5 ± 17.6 0.2
 Δ HR (beatsamin-1) 17.8 ± 6.3 28.3 ± 14.4 0.06
 HRR (%) 24.3 ± 11.5 28.3 ± 14.4 0.05
 Δ Borg 1.7 ± 1.9 3.9 ± 2.4 0.02
 Supplemental Oxygen (n, %) 1 (6.3) 2 (9.5) -
Lung function    
 FEV1 (% pred.) 93.9 ± 12.8 83.9 ± 10.6 0.02
 FEV1/FVC (% pred.) 95.8 ± 13.9 86.7 ± 9.2 0.03
 TLC (% pred.) 104.2 ± 15.2 105.2 ± 18.3 0.87
 VC (% pred.) 96.8 ± 14.0 92.1 ± 11.6 0.3
RHC   
 mPAP (mm Hg) 19.7 ± 3.2 36 ± 7.5 0.001
 RAP (mm Hg) 5.5 ± 2.4 8.7 ± 5.1 0.04
 PVR (dyneas/cm5) 218.3 ± 280.9 415.9 ± 163.7 0.012
 CI (l/min/m2) 2.9 ± 0.4 2.6 ± 0.6 0.09
 PAWP (mm Hg) 8.9 ± 3.8 12.2 ± 4.7 0.037
Echocardiography   
 TAPSE (mm) 18.3 ± 2.7 16.7 ± 3.6 0.2
 PASP (mm Hg) 50.6 ± 29.2 59.5 ± 21.9 0.5
CPETb    
 Peak VO2 (ml/min/kg) 15.2 ± 4.5 13.3 ± 3.9 0.36
 Rest VD/VT 30.3 ± 5.1 35.3 ± 6.4 0.35
 Peak VD/VT 27.7 ± 6.1 41.2 ± 12.1 0.13
 Rest VD, L 0.22 ± 0.07 0.37 ± 0.09 0.09
 Peak VD, L 0.63 ± 0.1 0.78 ± 0.26 0.39
 Rest SpO2 (%) 95.1 ± 1.3 93.7 ± 1.8 0.10
 Peak SpO2 (%) 89.1 ± 7.3 89.6 ± 4.6 0.86
 Δ SpO2 (%) −5.2 ± 5.4 −3.6 ± 3.3 0.69
 Rest HR (beatsamin-1) 76.1 ± 12.4 69.9 ± 11.7 0.15
 Peak HR (beatsamin-1) 125.3 ± 22.4 116.6 ± 19.9 0.25
 Δ HR (beatsamin-1) 49.2 ± 19.3 46.7 ± 19.9 0.72
 HRR (%) 55.1 ± 21.1 54.3 ± 21.8 0.92
Jamieson-Type, (%)   a 0.15
 I 14.2 46.7  
 II 42.9 20  
 III 42.9 33.3  
Laboratory   
 NT-proBNP (pg/ml) 175.0 [56–259] 389.0 [95–703] 0.18
  1. Values represent mean ± SD or median [IQR]. a = Pearson Chi-Square test, bn = 34. For abbreviations see Table 1