Table 4 Lipocalin-2 and syndecan-4 biomarkers at enrollment and corresponding variations after 5 days among 110 children hospitalized for radiologically confirmed community-acquired pneumonia according to their infection status

White blood cell at enrolment (cells/μL)

15,741 ± 8,575

16,573 ± 8,969

13,674 ± 7,338

14,358 ± 7,899

White blood cell after 5 days (cells/μL)^a

9,623 ± 4,437

9,546 ± 4,817

10,396 ± 2,726

9,471 ± 3,942

Variation in white blood cell (cells/μL)^a

−6,488 ± 9,680**

−7,505 ± 10,277**

−2,927 ± 8,310

−4,991 ± 7,899**

CRP at enrolment, μg/dL

25.5 ± 47.4

32.2 ± 55.5^***

9.4 ± 17.0^***

14.0 ± 19.4

CRP after 5 days, μg/dL^a

6.8 ± 17.4

9.4 ± 20.7^***

1.2 ± 1.9^***

1.7 ± 3.3

Variation in CRP, μg/dL^a

−20.2 ± 43.5**

−25.0 ± 51.4**

−6.6 ± 14.1**

−12.3 ± 16.7**

LIP2 at enrolment

2,079 ± 1,606

2,158 ± 1,744

1,880 ± 1,015

1,946 ± 1,488

LIP2 after 5 days

1,163 ± 1,015

1,195 ± 1,102

1,236 ± 828

986 ± 814

Variation in LIP2

−915 ± 1526**

−962 ± 1666**

−644 ± 583**

−959 ± 1532*

SYN4 at enrolment

5.08 ± 3.95

5.27 ± 4.10

4.31 ± 3.06

4.99 ± 4.14

SYN4 after 5 days

5.68 ± 4.29

5.71 ± 4.56

4.48 ± 3.08

6.53 ± 4.06

Variation in SYN4

0.59 ± 2.81

0.43 ± 2.75

0.17 ± 2.54

1.54 ± 3.17*