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Table 7 Logistic Regression Analysis adjusted by gender of the association between TLR4, TLR2 and CD14 SNPs and asthma

From: A case–control study of innate immunity pathway gene polymorphisms in Puerto Ricans reveals association of toll-like receptor 2 +596 variant with asthma

 

Males

Females

 

Adjusted OR

95 % CI

P-value

Adjusted OR

95 % CI

P-value

TLR4 +896

      

 AG

2.25

0.37-13.67

0.378

0.41

0.11-1.51

0.181

TLR4 +1196

      

 CT

3.56

0.50-25.56

0.206

0.48

0.13-1.84

0.286

TLR4 -6687

      

 AG

3.00

0.26-34.57

0.378

1.20

0.39-3.66

0.748

 AA

0.33

0.02-7.14

0.482

1.11

0.33-3.75

0.865

TLR2 +596

      

 CT

0.67

0.11-4.17

0.665

6.53

1.82-23.40

0.004

 TT

   

6.04

1.59-23.01

0.008

TLR2 -16934

      

 AT

   

2.40

0.85-6.73

0.096

 AA

0.13

0.02-0.90

0.039

0.90

0.27-3.00

0.864

TLR2 +399

      

 AG

0.60

0.12-2.89

0.525

2.30

0.93-5.67

0.070

 GG

   

0.74

0.18-3.05

0.678

TLR2 +1349

      

 CT

   

2.47

0.47-12.95

0.286

CD14 -159

      

 AG

1.94

0.29-13.19

0.496

0.73

0.29-1.85

0.503

 AA

2.79

0.36-21.73

0.325

1.00

0.28-3.54

1

CD14 +1188

      

 CG

   

0.72

0.28-1.90

0.513

  1. Legend: OR odds ratio, CI confidence interval