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Table 3 Comparison of drop-out rate mean values and reasons between RCTs and Real-life studies

From: Drop-out rate among patients treated with omalizumab for severe asthma: Literature review and real-life experience

 

RCT

Real-life

p-value

Drop-out

11.65 %

17.50 %

0.0000

Patient decision

59.72 %

35.01 %

0.0000

Lack of efficacy

0.69 %

23.53 %

0.0000

Adverse events

22.92 %

12.04 %

0.0011

Other causes

116.67 %

29.41 %

0.0016