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Fig. 4 | BMC Pulmonary Medicine

Fig. 4

From: Baicalin attenuates bleomycin-induced pulmonary fibrosis via adenosine A2a receptor related TGF-β1-induced ERK1/2 signaling pathway

Fig. 4

A2aR and baicalin attenuated TGF-β1 expression in the BLM mouse model. a Images of TGF-β1 immunohistochemistry in lung tissue sections. Magnification ×400, scale bars represent 100 μm. b Quantitative analysis of TGF-β1 protein by immunohistochemistry. c TGF-β1 content (pg/ml) of serum (ELISA) (n = 8). d Images of TGF-β1 in lung homogenate (western blot). e Quantitative analysis of TGF-β1 in lung by western blot. GAPDH was used as internal control (n = 3). Data were expressed as mean ± SD. ** p < 0.01 vs control group, * p < 0.05 vs control group, ## p < 0.01 vs model group, # p < 0.05 vs model group, ++ p < 0.01 between WT and KO groups, + p < 0.05 between WT and KO groups

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