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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: Acute exacerbation of IPF has systemic consequences with multiple organ injury, with SRA+ and TNF-α+ cells in the systemic circulation playing central roles in multiple organ injury

Fig. 1

Acute inflammatory lung injury of types 1 (a-c) and type 2 (d). a The exudative phase of diffuse alveolar damage with a hyaline membrane with neutrophils accumulation in alveolar septa and air spaces. b Alveolar epithelial cells absent from alveoli (arrow) and cytokeratin positive cell debris in air spaces. c Accumulation of platelets mostly in the capillaries of the alveolar septa. d Mild congestion, edema and extravasation with neutrophils accumulation in alveolar septa and air spaces. Scale bars: 30 μm (a-d). Immunohistochemistry for AE1/AE3 (b) and CD42b (c)

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