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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: Acute exacerbation of IPF has systemic consequences with multiple organ injury, with SRA+ and TNF-α+ cells in the systemic circulation playing central roles in multiple organ injury

Fig. 3

Findings in the heart (a, b) and peripheral blood (c, d). a Accumulation of platelets mostly in capillaries. b Marked reduction of ring-like or tube-like capillary structures, injured capillary endothelial cells have a ragged cytoplasm. c A large scavenger receptor-A positive cell. d A tumor necrosis factor-α-positive cell. Scal bars: 30 μm. Immunohistochemistry for CD42b (a), CD34 (b), scavenger receptor A (c), and tumor necrosis factor-α (d)

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