Combined pulmonary fibrosis and emphysema: a retrospective analysis of clinical characteristics, treatment and prognosis

Table 6 Univariate analysis: Relationship between clinical parameters and mortality in CPFE patients

Variable	P	Hazard ratio	95 % CI
BMI < 18 kg/m²	<0.01	5.64	2.68–11.89
Smoking	0.04	4.18	1–17.47
Diabetes	<0.01	5.19	2.51–10.75
Cardiovascular and cerebrovascular diseases	<0.01	4.68	1.65–13.28
Corpulmonale	<0.01	10.71	5.08–22.59
PAH	<0.01	27.68	8.35–91.81
Finger clubbing	<0.01	13.91	6.28–30.83
Increasing CEA level	<0.01	13.17	6.41–27.11
≥5-point increase of CPI per year	<0.01	45.03	15.19–133.52
≥5-score increase of HRCT per year	<0.01	4.63	2.47–8.71

Abbreviations: CPFE combined pulmonary fibrosis and emphysema, BMI body mass index, PAH pulmonary arterial hypertension, CEA carcinoembryonic antigen, CPI composite physiologic index, HRCT high-resolution computed tomography, CI confidence interval

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