Longitudinal trends in clinical characteristics and lung function of patients with severe asthma under treatment in Brazil

Table 1 Outline of procedures at each of the three main study visits

V0 – enrollment	V1 - 1 year later	V8 – 8 years later
Specialist evaluation with collection of information on health resource utilization in the last 12 months	Specialist evaluation	Specialist evaluation
Check for inclusion and non-inclusion criteria	Records of exacerbation history (emergency visits, hospitalizations and the use of systemic corticosteroids) in the last 12 months	Records of exacerbation history (emergency visits, hospitalizations and the use of systemic corticosteroids) in the last 12 months
Evaluation of rhinitis	Multidisciplinary approach to treatment and health education	Multidisciplinary approach to treatment and health education
Spirometry	Spirometry	Spirometry
Record of inhaled medications dispensation (at the beginning)	ACQ^a Questionnaire	ACQ^a Questionnaire
	AQLQ^b Questionnaire	AQLQ^b Questionnaire
	AQLQ^b Questionnaire	Skin prick test

Note: ^aAsthma Control Questionnaire (ACQ) [24, 25], ^bAsthma Quality of Life Questionnaire (AQLQ) [26, 27]

ISSN: 1471-2466