Table 7 Trends in post-bronchodilator (PostBD) spirometric parameters during follow up

FVC L

2.7 (2.3–3.5)

2.8 (2.3–3.4)

2.6 (2.1–3.1)

0.98

<0.01

FVC (% pred)

91.0 (77.0–101.0)

91.0(79.0–102.0)

82.2 (73.6–92.0)

0.43

<0.01

FEV₁ (L)

1.9 (1.4–2.3)

1.9 (1.5–2.4)

1.7 (1.3–2.2)

0.41

<0.01

FEV₁ (%pred)

73.0 (60.0–85.0)

73.0 (63.0–86.0)

67.2 (56.3–80.3)

0.15

<0.01

FEV₁/FVC

0.7 (0.6–0.8)

0.7 (0.6–0.8)

0.7 (0.6–0.7)

0.34

0.21

FEV₁/FVC (%pred)

82.0 (68.0–93.0)

83.0 (71.0–92.0)

81.5 (74.7–91.4)

0.23

0.41

FEF_25–75% (L/s)

1.0 (0.6–1.6)

1.1 (0.6–1.8)

1.0 (0.7–1.6)

0.04

<0.01

FEF_25–75% (%pred)

34.0 (22.0–57.0)

41.0 (25.0–64.0)

37.8 (29.9–62.7)

0.04

0.88

BD chg (ml)

290.0(180.0–440.0)

160.0(40.0–340.0)

170.0(70.0–300.0)

<0.01

0.87

BD chg (%)

18.0 (11.0–28.0)

10.0 (2.0–22.0)

11.6 (5.0–20.7)

<0.01

0.10