Fig. 2
From: Targeted high-throughput sequencing of candidate genes for chronic obstructive pulmonary disease
CHRNA5 gene expression levels in the lungs according to genotype groups for rs8040868. The left y-axis represents standardised gene expression levels in the lung with heterozygous genotype group set to zero. The x-axis represents the three genotyping groups, TT, CT and CC (risk allele C), for the variant in (a) the discovery set (Laval) n = 408; P = 4.2 × 10−10, and the replication sets (b) UBC, n = 287; P = 2.31 × 10−7, and (c) Groningen, n = 342; P = 1.5 × 10−6. The number of subjects per genotype group is indicated in parenthesis. The right y-axis shows the proportion of the gene expression variance explained by the variant (black bar)