Table 2 Cox model measure hazard ratios and 95% confidence intervals of asthma associated with primary Sjögren’s syndrome and covariates
From: Risk of asthma in patients with primary Sjögren’s syndrome: a retrospective cohort study
Variables | Events | IR | HR (95% CI) | |
|---|---|---|---|---|
Univariate | Multivariatea | |||
Primary SS | ||||
No | 844 | 6.10 | 1.00 | 1.00 |
Yes | 337 | 9.86 | 1.62 (1.42 − 1.83)*** | 1.38 (1.21 − 1.58)*** |
Sex | ||||
Women | 1007 | 6.62 | 1.00 | 1.00 |
Men | 174 | 8.45 | 1.26 (1.07 − 1.48)** | 0.90 (0.76 − 1.06) |
Age, years | ||||
20 − 39 | 134 | 3.95 | 1.00 | 1.00 |
40 − 59 | 504 | 5.61 | 1.41 (1.17 − 1.71)*** | 1.41 (1.16 − 1.70)*** |
≥ 60 | 543 | 11.1 | 2.74 (2.27 − 3.31)*** | 2.65 (2.19 − 3.22)** |
Comorbidity | ||||
Allergic rhinitis | ||||
No | 952 | 6.13 | 1.00 | 1.00 |
Yes | 229 | 13.1 | 2.08 (1.80 − 2.41)*** | 1.76 (1.51 − 2.06)*** |
Chronic sinusitis | ||||
No | 1116 | 6.61 | 1.00 | 1.00 |
Yes | 65 | 17.5 | 2.58 (2.01 − 3.32)*** | 1.71 (1.31 − 2.22)*** |
Atopic dermatitis | ||||
No | 1153 | 6.77 | 1.00 | 1.00 |
Yes | 28 | 11.8 | 1.67 (1.15 − 2.43)** | 1.39 (0.95 − 2.02) |
COPD | ||||
No | 1123 | 6.58 | 1.00 | 1.00 |
Yes | 58 | 29.8 | 4.30 (3.30 − 5.60)*** | 2.52 (1.91 − 3.33)*** |
GERD | ||||
No | 1167 | 6.80 | 1.00 | 1.00 |
Yes | 14 | 15.2 | 2.03 (1.20 − 3.41)** | 1.28 (0.75 − 2.17) |
Obesity | ||||
No | 1171 | 6.81 | 1.00 | 1.00 |
Yes | 10 | 14.1 | 2.02 (1.09 − 3.77)* | 2.05 (1.10 − 3.82)* |