BMC Pulmonary Medicine

Table 3 Incidence density rates and hazard ratios of asthma according to primary Sjögren’s syndrome status stratified by sex, age, and comorbidity

From: Risk of asthma in patients with primary Sjögren’s syndrome: a retrospective cohort study

	No-SS group			Primary SS group			Compared to the non-SS group
	No-SS group			Primary SS group			HR (95% CI)
Variables	Events	Person-years	IR	Events	Person-years	IR	Relative	Adjusted^b
Sex
Women	720	121936	5.90	287	30090	9.54	1.61 (1.41 − 1.85)***	1.39 (1.21 − 1.60)***
Men	124	16497	7.52	50	4104	12.2	1.63 (1.17 − 2.27)**	1.31 (0.92 − 1.86)
Age, years
20 − 39	87	27166	3.20	47	6797	6.91	2.17 (1.52 − 3.09)***	1.80 (1.24 − 2.60)**
40 − 59	351	72063	4.87	153	17771	8.61	1.77 (1.46 − 2.13)***	1.54 (1.26 − 1.87)***
≥ 60	406	39204	10.4	137	9626	14.2	1.37 (1.13 − 1.67)**	1.16 (0.95 − 1.42)
Comorbidity status^a
No	658	123800	5.32	196	25269	7.76	1.47 (1.25 − 1.72)***	1.47 (1.25 − 1.72)***
Yes	186	14633	12.7	141	8925	15.8	1.25 (1.01 − 1.56)*	1.24 (0.99 − 1.54)

CI confidence interval, HR hazard ratio, IR incidence density rate per 1000 person-years, SS Sjögren’s syndrome
^aIndividuals with any one of allergic rhinitis, chronic sinusitis, atopic dermatitis, chronic obstructive pulmonary disease, gastroesophageal reflux disease, and obesity were classified as the comorbidity group
^bModel was adjusted for sex, age and comorbidity in Cox proportional hazards regression
*p <0.05, **p <0.01, ***p <0.001

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ISSN: 1471-2466

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