Table 2 Diagnostic accuracy of symptoms and rapid testing for diagnosing culture-confirmed pulmonary tuberculosis.
Sensitivity | Specificity | Positive PV | Negative PV | |||
|---|---|---|---|---|---|---|
Positive/Total | % (95% CI) | Negative/Total | % (95% CI) | % (95% CI) | % (95% CI) | |
Existing screening algorithms | ||||||
Cough | 66/123 | 54 (44–63) | 376/552 | 68 (64–72) | 27 (22–33) | 87 (83–90) |
Any TB-related Symptoma | 95/123 | 77 (69–84) | 222/552 | 40 (36–44) | 22 (18–27) | 89 (84–92) |
Any TB-related Symptoma or Abnormal chest x-ray | 102/123 | 83 (75–89) | 219/552 | 40 (36–44) | 23 (20–28) | 91 (87–95) |
Urine LAM alone | ||||||
Urine LAM Test Positive | 38/123 | 31 (23–39) | 508/552 | 92 (89–94) | 46 (35–58) | 86 (83–88) |
Adding urine LAM to existing screening algorithms | ||||||
Cough or Urine LAM Positive | 84/123 | 68 (59–76) | 353/552 | 63 (60–68) | 30 (24–35) | 90 (87–93) |
Any TB-related Symptoma or Urine LAM Positive | 102/123 | 83 (75–89) | 205/552 | 37 (33–41) | 23 (19–27) | 91 (86–94) |
Any TB-related Symptoma or Abnormal chest x-ray or Urine LAM Positive | 107/123 | 87 (80–92) | 208/552 | 38 (34–42) | 24 (20–28) | 93 (89–96) |