Combined ultrasound-guided cutting-needle biopsy and standard pleural biopsy for diagnosis of malignant pleural effusions

Table 3 Comparison of diagnostic accuracy between US-guided biopsy and standard biopsy

	CNB (n = 156)	SPB (n = 160)	CNB + SPB (n = 166)	Statistical significance
FN	40	30	10	NA
TN	74	78	78	NA
TP	42	52	78	NA
FP	0	0	0	NA
Sensitivity	51.2%	63.4%	88.6%	p = 0.147, 0.000, 0.000*
Specificity	100%	100%	100%	NA
PPV	100%	100%	100%	NA
NPV	64.9%	72.2%	88.6%	p = 0.394, 0.000, 0.009*
Diagnostic accuracy	74.4%	81.3%	93.9%	p = 0.341, 0.001, 0.017*

CNB cutting-needle biopsy, FN false-negative, FP false-positive, NA not applicable, NPV negative-predictive value, PPV positive-predictive value, SPB standard pleural biopsy, TN true-negative, TP true-positive, US ultrasound
*p-values for CNB vs SPB; CNB + SPB vs CNB; and CNB + SPB vs SPB

ISSN: 1471-2466