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Table 1 Anthropometric data, pulmonary function, normoxic resting ventilation and hypoxic ventilatory response (HVR) in non-smokers (NSM) and smokers (SM)

From: Lower hypoxic ventilatory response in smokers compared to non-smokers during abstinence from cigarettes

  

NSM

SMa

P

n

 

23

23

Cigarettes per day

(n d−1)

-

29.6 ± 1.6

-

Pack yearsb

(years)

-

16.8 ± 2.7

-

Age

(years)

32.7 ± 1.7

33.9 ± 2.0

0.644

Body weight

(kg)

78.8 ± 2.5

80.3 ± 1.9

0.632

Body height

(m)

1.80 ± 1.7

1.81 ± 1.2

0.655

BMI

(kg m−2)

24.2 ± 0.6

24.2 ± 0.5

0.980

RR systolic

(mmHg)

124.5 ± 1.9

129.6 ± 1.8

0.055

RR diastolic

(mmHg)

79.0 ± 1.9

83.0 ± 1.4

0.93

VC

(l)

5.2 ± 0.2

5.3 ± 0.2

0.847

VC relative

(%)

95.9 ± 3.9

95.1 ± 3.0

0.870

FVC relative

(%)

108 ± 4

104 ± 4

0.535

FEV1%VC

(%)

78.9 ± 2.0

78.0 ± 2.9

0.803

FEV1 relative

(%)

106.8 ± 4.8

101.2 ± 4.5

0.407

FEV1%VCrelative

(%)

97.7 ± 2.7

96.3 ± 3.6

0.744

Ventilation

(l min−1)

9.2 ± 0.3

8.0 ± 0.3

0.006c

Tidal volume

(ml)

828 ± 56

951 ± 93

0.264

Respirat. frequency

(min−1)

12.2 ± 1.0

9.9 ± 0.8

0.078

PetCO2

(mmHg)

39.3 ± 0.5

39.2 ± 0.7

0.957

PetO2

(mmHg)

101.4 ± 1.1

99.4 ± 1.1

0.218

VCO2

(ml min−1)

253 ± 8

233 ± 7

0.058

VO2

(ml min−1)

304 ± 8

291 ± 8

0.268

RQ

(ratio)

0.83 ± 0.01

0.79 ± 0.02

0.088

SaO2

(%)

99.1 ± 0.2

99.0 ± 0.2

0.705

HVR

(l min−1 %−1)

0.89 ± 0.08

0.58 ± 0.05

0.003c

HVR a BMI−1

(l min−1 %−1kg−1 m−2)

0.037 ± 0.003

0.024 ± 0.002

0.002c

PetCO2 HVR

(mmHg)

38.8 ± 0.4

38.8 ± 0.6

0.959

  1. Mean ± S.E.M. a>15 cigarettes/day for >8 years with nicotine >0.5 mg and tar >6 mg
  2. bcumulative years of 20 cigarettes/day. c for P < 0.01. BMI Body mass index, VC vital capacity, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, PetCO 2 and PetCO 2 end-tidal partial pressures of CO2 and O2, respectively (BTPS), VCO 2 CO2 output, VO 2 O2 uptake, RQ Respiratory quotient, i.e. VCO2 to VO2 ratio, SaO 2 peripheral arterial O2-saturation, HVR hypoxic ventilatory response, PetCO 2 HVR mean PetCO2 during HVR measurement