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Table 2 Blood cardiovascular risk factors in non-smokers (NSM) and smokers (SM): plasma lipids, oxidized LDL, basal glucose, extra- and intracellular thiol redox state, adhesion molecules and TNF-α

From: Lower hypoxic ventilatory response in smokers compared to non-smokers during abstinence from cigarettes

 

NSM

SMa

P

Triglycerides

(mg 100 ml−1)

66.4 ± 5.7

94.0 ± 7.5

0.005c

Total cholesterol

(mg 100 ml−1)

178 ± 7

206 ± 8

0.016b

VLDL

(mg 100 ml−1)

14.3 ± 1.2

23.1 ± 3.1

0.012b

LDL

(mg 100 ml−1)

121 ± 7

140 ± 9

0.094

oxLDL

(U l−1)

52.9 ± 5.4

88.6 ± 13.6

0.021b

HDL

(mg 100 ml−1)

44.3 ± 1.8

45.3 ± 2.6

0.734

Glucose

(mg 100 ml−1)

79.7 ± 2.8

73.5 ± 2.7

0.115

HbA1c

(%)

5.30 ± 0.07

5.25 ± 0.06

0.590

Homocysteine

(μM)

9.0 ± 0.5

9.2 ± 0.5

0.715

Cysteine

(μM)

7.66 ± 0.32

7.47 ± 0.35

0.687

Cystine

(μM)

40.8 ± 1.1

43.3 ± 1.2

0.126

GSHintracellular

(nmol mg−1)

15.3 ± 2.2

18.3 ± 1.8

0.303

GSSGintracellular

(nmol mg−1)

2.94 ± 0.42

2.37 ± 0.50

0.397

ICAM-1

(ng ml−1)

378 ± 30

533 ± 35

0.002c

VCAM-1

(ng ml−1)

791 ± 47

726 ± 40

0.297

TNF-α

(pg ml−1)

24.3 ± 4.8

22.4 ± 2.0

0.717

  1. Mean ± S.E.M.; a>15 cigarettes/day for >8 years with nicotine >0.5 mg and tar >6 mg
  2. bfor P < 0.05, cfor P < 0.01. OxLDL oxidized LDL, GSH reduced glutathione, GSSG glutathione-disulphide in peripheral blood mononuclear cells, ICAM-1 intercellular adhesion molecule 1, VCAM-1 vascular adhesion molecule 1, TNF-α tumor necrosis factor alpha