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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: Clinical, physiologic, and radiographic factors contributing to development of hypoxemia in moderate to severe COPD: a cohort study

Fig. 3

Development of hypoxemia is associated with worsened QOL and reduced exercise tolerance. Compared to normoxic participants at Phase 2, participants who developed hypoxemia had a greater rate of change in a SGRQ total score, b SGRQ activity score, c SGRQ impact score, but no difference of change in d SGRQ symptom score or breathlessness measured by e MMRC. Likewise, these participants have a greater decrease in f 6MWD change compared to participants who remained normoxic. Error bars represent standard error. SGRQ = St George’s Respiratory Questionnaire, 6MWD = 6-min walk distance. MMRC = modified medical research council score. *P < 0.05, **P < 0.01, ***P < 0.001

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