Table 8 Natriuretic peptide levels in patients with COPD stratified by severity
From: B-type natriuretic peptides in chronic obstructive pulmonary disease: a systematic review
| Â | n | Population | Natriuretic peptide (pg/ml) | Median or mean peptide level according to GOLD I/II/III/IV | Significant difference across GOLD groups |
|---|---|---|---|---|---|
Rutten [24] | 118 | stable | NT-proBNP | ~127/119/136/169 | p = NS |
Watz [30] | 170 | stable | NT-proBNP | 69/62/67/73 | p = 0.78 |
Inoue [35] | 60 | stable | BNP | ~30/30/50/65 | p < 0.01 |
van Gestel [49] | 144 | stable | NT-proBNP | 212/170/352/– |  |
Mansour [86] | 57 | stable | BNP | excluded/38/60/78 | p < 0.05 |
Chi [84] | 61 | stable | NT-proBNP | excluded/112/151/250 | p = 0.02 |
Nishimura [36] | 190 | stable | BNP | 18/26/22/17 | p = 0.53 |
Rubinsztajn [77] | 81 | stable | NT-proBNP | 114/232/155/231 | p = NS |