Fig. 2
Pooled effects for efficacy endpoints with 95% CI of eligible studies comparing small versus standard size particle ICS medications. Mean difference in change from baseline between treatments for (a) FEV1, (b) morning PEF and (c) FEF25%-75%. BDP, beclometasone dipropionate, BDP-F, beclometasone dipropionate/formoterol fumarate; CI, confidence interval; CIC, ciclesonide; FEF25–75%, % predicted forced expiratory flow between 25% and 75% of forced vital capacity; FEV1, forced expiratory volume in 1 s; FP, fluticasone propionate; FP/SAL, fluticasone propionate/salmeterol; PEF, peak expiratory flow