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Table 1 Characteristics of the patient groups with and without apnea episodes (n = 121)

From: End-tidal capnographic monitoring to detect apnea episodes during flexible bronchoscopy under sedation

Variable

With apnea episodes (n = 59)

Without apnea episodes (n = 62)

P value

Age (years), median (range)

71 (23–82)

69 (37–81)

0.781

Gender (male), n (%)

40 (67.8)

42 (67.7)

0.995

BMI (kg/m2), mean ± SD

22.3 ± 2.8

21.3 ± 2.9

0.061

ASA physical status (I/II/III/IV), n

15/36/8/0

25/31/6/0

0.214

Comorbidities and diagnoses, n (%)

 COPD

1 (1.7)

4 (6.5)

0.365

 ILD

11 (18.6)

8 (12.9)

0.458

 Infectious disease

3 (5.1)

3 (4.8)

1.000

 Malignancy

41 (69.5)

39 (62.9)

0.565

 Others

12 (20.3)

11 (17.7)

0.818

Procedures, (%)

 Endobronchial biopsy

16.9

12.9

0.532

 Brushing

42.4

56.5

0.122

 TBB

54.2

64.5

0.250

 TBNA

25.4

19.4

0.423

 Washing

15.3

29.0

0.069

Baseline SpO2 a (%), mean ± SD

97.1 ± 1.0

98.0 ± 1.0

0.014

Minimum SpO2 b (%), median (IQR)

89 (87–93)

96 (92–97)

<0.001

Maximum O2 flow (L/min), median (IQR)

2 (2–4)

2 (2-2)

<0.001

Total dose of midazolam (mg), mean ± SD

3.9 ± 1.0

2.3 ± 0.8

<0.001

  1. BMI body mass index, SD standard deviation, ASA American Society of Anesthesiologists, COPD chronic obstructive pulmonary disease, ILD interstitial lung disease, TBB transbronchial biopsy, TBNA transbronchial needle aspiration (including endobronchial ultrasound-guided aspiration), IQR interquartile range
  2. aBefore flexible bronchoscopy in ambient air
  3. bDuring flexible bronchoscopy under supplemental oxygen