Table 2 Results of fitting the model to 20 ARDS patient data of PaO2, PaCO2 and Cstat at baseline
From: Hemodynamic effects of lung recruitment maneuvers in acute respiratory distress syndrome
| Â | Â | All Patients | Severe ARDS | Moderate ARDS | Mild ARDS | ||||
|---|---|---|---|---|---|---|---|---|---|
| Â | n | 20 | 11 | 6 | 3 | ||||
|  | Vt (ml kg−1) | 6 | |||||||
|  | VR (b min−1) | 12 | |||||||
| Â | PEEP (cm H2O) | 10 | |||||||
| Â | Ventilation mode | Volume controlled | |||||||
| Â | FIO2 | 1 | |||||||
| Â | HR (bpm) | 100 | |||||||
| Â | Â | mean | sd | mean | sd | mean | sd | mean | sd |
Parameters determined by optimizationa | CI (l min−1 m−2) | 5.3 | 0.5 | 5.0 | 0.4 | 5.6 | 0.5 | 6.0 | 0.1 |
RQ | 0.8 | 0.1 | 0.8 | 0.1 | 0.8 | 0.1 | 0.8 | 0.1 | |
VO2 (ml min−1) | 304.4 | 6.3 | 305.8 | 3.8 | 303.8 | 8.0 | 300.3 | 10.6 | |
Duty Cycle | 0.4 | 0.0 | 0.4 | 0.0 | 0.4 | 0.0 | 0.4 | 0.0 | |
Hb (g l−1) | 110.5 | 39.5 | 92.5 | 32.6 | 115.8 | 33.9 | 165.7 | 13.5 | |
Results of fitting the model to the data | PaO2 (mm Hg) | 120.9 | 73.2 | 68.6 | 10.6 | 149.5 | 36.1 | 255.3 | 49.7 |
Cstat (ml/cm H2O) | 25.0 | 6.4 | 22.0 | 4.5 | 27.3 | 4.5 | 31.7 | 10.1 | |
PaCO2 (mmHg) | 61.2 | 3.6 | 59.3 | 2.9 | 62.3 | 3.3 | 65.7 | 1.2 | |
Other results | Shunt Fraction (%) | 37.6 | 12.3 | 46.5 | 5.0 | 30.8 | 5.5 | 18.7 | 11.7 |
| Â | Pplat (cm H2O) | 27.4 | 4.1 | 29.4 | 4.1 | 25.3 | 2.1 | 24.0 | 4.4 |
| Â | TOP (cm H2O) | 21.6 | 2.4 | 22.3 | 2.8 | 21.0 | 2.0 | 20.0 | 0.0 |