Table 4 Change From Baseline to Weeks 12 and 24 in Functional Class (LOCF)
Change, n (%) | Sildenafil Dose, TID | |||||
|---|---|---|---|---|---|---|
Double-Blind Phase (Week 12) | Open-Label Phase (Week 24) | |||||
1 mg (n = 41) | 5 mg (n = 43) | 20 mg (n = 45) | 1 mg (n = 41) | 5 mg (n = 43) | 20 mg (n = 45) | |
Worsened 2 classes | 0 | 0 | 0 | 0 | 0 | 1 (2) |
Worsened 1 class | 1 (2) | 3 (7) | 2 (4) | 0 | 3 (7) | 1 (2) |
No change | 35 (85) | 27 (63) | 35 (78) | 23 (56) | 19 (44) | 22 (49) |
Improved 1 class | 4 (10) | 10 (23) | 6 (13) | 11 (27) | 13 (30) | 11 (24) |
Improved 2 classes | 1 (2) | 0 | 0 | 1 (2) | 1 (2) | 1 (2) |
Missing | 0 | 3 (7) | 2 (4) | 6 (15) | 7 (16) | 9 (20) |