Hemosiderin-laden macrophages are an independent factor correlated with pulmonary vascular resistance in idiopathic pulmonary fibrosis: a case control study

Table 4 Univariate analysis between PVR and baseline characteristics

Characteristics	t	ρ	P-value
Age		0.230	0.020
Gender (male)	−1.035		0.305
Smoking history (smokers)	−1.279		0.207
BNP		−0.091	0.361
FVC, % pred		−0.124	0.211
D_LCO,% pred		−0.518	< 0.001
PaO₂		−0.424	< 0.001
PaCO₂		−0.167	0.091
Six-minute walk distance		−0.583	< 0.001
Min-SpO₂		−0.318	0.001
BALF-neutrophils, %		0.142	0.152
BALF-lymphocytes, %		0.098	0.325
BALF-eosinophils, %		0.113	0.255
HLM score		0.349	< 0.001

Definitions of abbreviations: PVR pulmonary vascular resistance, t Student’s t, ρ Spearman’s correlation coefficient, BNP brain natriuretic peptide, FVC forced vital capacity, % pred percent of normal predicted value, D _L CO diffusing capacity of the lung for carbon monoxide, PaO ₂ partial pressure of oxygen in arterial blood, PaCO ₂ partial pressure of carbon dioxide in arterial blood, min-SpO ₂ minimum oxygen saturation during 6-min walk test, BALF bronchoalveolar lavage fluid, HLM hemosiderin-laden macrophage

ISSN: 1471-2466