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Table 5 Prognosis of asthma phenotypes according to asthma clusters

From: Persistent asthma phenotype related with late-onset, high atopy, and low socioeconomic status in school-aged Korean children

Variables

Cluster 1

Cluster 2

Cluster 3

Cluster 4

P value

New-onset BHR, n (%)

8/21 (38.1)

1/17 (5.9)

3/5 (60.0)

5/64 (7.8)*

<0.001

Persistence of BHR, n (%)

12/20 (60.0)

1/7 (14.3)

7/15 (46.7)

2/22 (9.1)*

<0.002

Remission of BHR, n (%)

8/20 (40.0)

6/7 (85.7)

8/15 (53.3)

20/22 (90.9)*

0.002

Wheezing in the previous 12 months at follow-up, n (%)

4/23 (17.4)

10/26 (38.5)

13/24 (54.2)

3/25 (12.0)†

0.005

New-onset AR, n (%)

9/18 (50.0)

6/9 (66.7)

7/15 (46.7)

15/60 (25.0)

0.026

New sensitization on SPT

13/42 (31.0)

4/26 (15.4)

6/23 (26.1)

27/91 (29.7)

0.493

  1. Definition of abbreviations: AR allergic rhinitis, BHR methacholine PC20 < 8 mg/ml, SPT skin prick test
  2. * P value < 0.005, compared with cluster 1
  3. † P value < 0.005, compared with cluster 3