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Table 5 Prevalence ratio and relative risk (crude and adjusted analysis) for exacerbations, hospitalisations due to exacerbation in the past year and mMRC scale in the different phenotypes

From: Asthma–COPD overlap syndrome (ACOS) in primary care of four Latin America countries: the PUMA study

 

Asthma

p-value

COPD

ACOS

p-value

Asthma defined by wheezing + reversibility

 Exacerbations in the past year (yes/no)

  Unadjusted – PR (95% CI)

1.85 (0.85; 4.06)

0.122

1.00

2.68 (1.30; 5.52)

0.007

  Adjusteda– PR (95% CI)

2.24 (0.92; 5.45)

0.075

1.00

2.20 (1.10; 4.39)

0.026

 Number of exacerbations in the past year

  Unadjusted – RR (95% CI)

1.77 (0.72; 4.34)

0.210

1.00

2.10 (0.90; 4.90)

0.086

  Adjusteda– RR (95% CI)

2.84 (0.94; 8.61)

0.065

1.00

1.64 (0.78; 3.44)

0.191

 Hospitalisations in the past year

  Unadjusted – PR (95% CI)

0.76 (0.10; 5.96)

0.795

1.00

2.89 (0.80; 10.39)

0.104

  Adjusteda– PR (95% CI)

3.57 (0.48; 26.59)

0.214

1.00

1.65 (0.53; 5.06)

0.385

 mMRC scale

  Unadjusted – RR (95% CI)

0.64 (0.41; 0.99)

0.289

1.00

1.17 (0.88; 1.56)

0.046

  Adjusteda– RR (95% CI)

0.73 (0.48; 1.12)

0.149

1.00

1.22 (0.92; 1.12)

0.176

Asthma defined as medical diagnosis

 Exacerbations in the past year (yes/no)

  Unadjusted – PR (95% CI)

1.80 (1.01; 3.20)

0.046

1.00

1.80 (0.91; 3.53)

0.089

  Adjusteda– PR (95% CI)

1.57 (0.75; 3.27)

0.231

1.00

1.29 (0.64; 2.60)

0.480

 Number of exacerbations in the past year

  Unadjusted – RR (95% CI)

1.92 (0.99; 3.68)

0.054

1.00

1.68 (0.77; 3.66)

0.191

  Adjusteda– RR (95% CI)

2.01 (0.94; 4.30)

0.072

1.00

1.32 (0.60; 2.88)

0.490

 Hospitalisations in the past year

 Unadjusted – PR (95% CI)

0.58 (0.16; 2.16)

0.419

1.00

1.07 (0.29; 3.92)

0.923

 Adjusteda– PR (95% CI)

0.68 (0.17; 2.69)

0.581

1.00

0.72 (0.21; 2.44)

0.596

 mMRC scale

  Unadjusted – RR (95% CI)

0.90 (0.72; 1.14)

0.311

1.00

1.24 (0.98; 1.56)

0.052

  Adjusteda– RR (95% CI)

0.97 (0.75; 1.25)

0.799

1.00

1.20 (0.96; 1.21)

0.108

  1. aAdjusted for age, sex, skin colour, body mass index, schooling, comorbidity score, pack-years and any treatment (bronchodilator or corticosteroid)
  2. Abbreviations: PR prevalence ratio, RR relative risk