Table 1 Demographic and clinical characteristics of copd patients and controls

Age

65.9 (7.4)

67.6 (8.4)

0.4466¹

Males (%)

45.8

58.1

0.4224²

Height (m)

1.7 (0.1)

1.7 (0.1)

0.7358¹

Body mass index

26.8 (4.6)

26.2 (4.6)

0.6783¹

Smoking (pack years

0.0 (3.0)

54.0 (28.0)

<0.0001³****

Cardiovascular risk (FRSP)

6.2 (3.2)

7.4 (4.1)

0.2488¹

Exacerbations in last 12 months

-

1.0 (3.0)

-

Health status (SGRQ)

-

54.3 (30.3)

-

Co-morbidity Index

0 (0)

0 (1)

0.0039³**

HADs – Anxiety

4.0 (2.8)

7.3 (4.5)

0.0031^1a**

HADs – Depression

2.9 (2.8)

5.5 (3.7)

0.0068¹**

HADs – Total

7.0 (5.0)

11.5 (16.0)

0.0128^1a*

 Estimated pre-morbid IQ

110.0 (15.5)

103.0 (16.0)

0.0061³**

 Executive Function

12.2 (2.6)

9.3 (2.5)

<0.0001¹****

 Episodic Memory

10.9 (3.1)

9.1 (2.5)

0.0226¹*

 Processing Speed

108.0 (19.5)

88.0 (24.0)

0.0008³***

 Working memory

107.0 (15.3)

94.1 (12.3)

0.0011¹**

 MMSE

29.5 (1.0)

28.0 (2.0)

0.0002³***

 FEV₁ (% pred.)

-

52.1 (20.9)

-

 FVC (% pred.)

-

84.8 (32.1)

-

 FEV₁/FVC (%)

-

49.2 (30.0)

-

 PaO₂ (kPa)

-

10.1 (2.2)

-

 PaCO₂ (kPa)

-

5.0 (0.7)

-

 pH

-

7.4 (0.0)

-