Table 4 Within-group correlations between whole-brain and hippocampal measures, and cognitive and disease severity indices

Executive Function

−0.4693

0.2547^b

0.3229

1.0000^b

−0.0977

1.0000^b

−0.4149

0.5513^b

−0.2539

1.0000^b

Episodic Memory

−0.1129

1.0000^b

−0.0970

1.0000^b

−0.0937

1.0000^b

0.0196

1.0000^b

0.0279

1.0000^b

Processing Speed

−0.0805

1.0000^b

−0.0330

1.0000^b

−0.0574

1.0000^b

0.1668

1.0000^b

−0.0307

1.0000^b

Working memory

−0.3878

0.6591^b

−0.1026

1.0000^b

−0.2782

1.0000^b

−0.2139

1.0000^b

−0.1739

1.0000^b

MMSE

−0.3250

1.0000^b

0.0473

1.0000^b

−0.0298

1.0000^b

0.1738

1.0000^b

−0.1146

1.0000^b

 Executive Function

0.1546

1.0000^b

0.0120

1.0000^b

0.0353

1.0000^b

−0.0718

1.0000^b

−0.1532

1.0000^b

 Episodic Memory

0.0016

1.0000^b

0.0900

1.0000^b

0.0206

1.0000^b

−0.2820

1.0000^b

0.4397

0.1537^b

 Processing Speed

0.0630

1.0000^b

0.1093

1.0000^b

0.0854

1.0000^b

−0.1720

1.0000^b

−0.0054

1.0000^b

Working memory

0.1646

1.0000^b

0.2304

1.0000^b

0.2191

1.0000^b

−0.1680

1.0000^b

0.0197

1.0000^b

 MMSE

−0.1320

1.0000^b

0.2896

1.0000^b

0.1503

1.0000^b

−0.4139

0.2550^b

0.0034

1.0000^b

 Pack Years

0.1648

1.0000^b

−0.0098

1.0000^b

0.0962

1.0000^b

0.0236

1.0000^b

−0.1153

1.0000^b

 Exacerbation

Frequency

0.0211

1.0000^b

−0.0929

1.0000^b

0.0491

1.0000^b

0.0695

1.0000^b

0.5089

0.0385^b*

 FEV₁ (% pred.)

−0.2432

1.0000^b

−0.2142

1.0000^b

−0.3895

0.3240^b

−0.1661

1.0000^b

0.1928

1.0000^b

 FVC (% pred.)

−0.0939

1.0000^b

0.0331

1.0000^b

−0.0031

1.0000^b

−0.2095

1.0000^b

0.2213

1.0000^b

 PaO₂ (KPa)

0.1599

1.0000^b

−0.1375

1.0000^b

−0.1249

1.0000^b

0.0497

1.0000^b

−0.0963

1.0000^b

 PaCO₂ (Kpa)

−0.0397

1.0000^b

0.3203

0.7722^b

0.2792

1.0000^b

−0.1540

1.0000^b

−0.0804

1.0000^b

 SGRQ

0.1961

1.0000^b

−0.1271

1.0000^b

0.0454

1.0000^b

0.2410

1.0000^b

−0.1185

1.0000^b