Fig. 1

The alterations of pulmonary indicators in different treated groups at different times after surgery. a, the alteration of PaO₂ in different groups after surgery; b, the alteration of aterial pH in different groups after surgery; c, the alteration of PaCO₂ in different groups after surgery; d, the alteration of peak airway pressure in different group after surgery; e, the alteration of lung compliance in different groups after surgery; f the alteration of MAP in different groups after surgery. For control group (n = 8), rabbits only received saline intratracheally injection (2.8 ml/kg) after surgery; for HCl groups (n = 8), ALI model was established by intratracheal injection of HCl (pH 1.5, 2.8 ml/kg); for VNS groups (n = 8), after the ALI model established by HCl, rabbits also received constant voltage stimuli (5 V, 2 ms, and 1 Hz); for THA group (n = 8), after ALI model established by HCl, rabbits also received THA (3 mg/kg) intravenous injection; and for SGB group, after ALI model established by HCl, rabbits also continuously received 0.25% bupivacaine pumping via epidural catheter (3 mg/kg). VNS, vagus nerve stimulation; THA, tetrahydroaminoacridine; SGB, stellate ganglion block; ALI, acute lung injury; MAP, mean arterial pressure