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Table 4 Pathogens detected by blood culture or by SeptiFast polymerase chain reaction analysis, and their clinical relevance

From: Bacteraemia and fungaemia in cystic fibrosis patients with febrile pulmonary exacerbation: a prospective observational study

Pathogen

SF

BC

Probably contaminant

Pathogen

in sputuma

Therapeutic

intervention

Comment

C. albicans

+

+

-

+

Fluconazole i.v.

Totally implantable venous access port; sepsis

C. albicans

+

+

-

+

Fluconazole i.v.

Central venous line; candida culture at top of line positive; sepsis

S. maltophilia

+

-

-

+

Trimethoprim/sulfamethoxazole

i.v.

Intermittent respiratory tract colonization with S. maltophilia

P. aeruginosa

+

-

-

+

-

Intermittent respiratory tract colonization with P. aeruginosa; P. aeruginosa antibodies negative; empiric antibiotic treatment covered P. aeruginosa

P. aeruginosa

+

-

-

+

-

Chronic respiratory tract infection with P. aeruginosa; empiric antibiotic treatment covered P. aeruginosa

K. pneumoniae

+

-

-

-

-

Empiric antibiotic treatment covered K. pneumonia

S. aureus

-

+

-

Intermittent

-

Erysipelas, left foot; Empiric treatment covered S. aureus

E. cloacae

+

-

+

-

-

 

E. cloacae

+

-

+

-

-

 

S. epidermidis

-

+

+

-

-

 

S. epidermidis

-

+

+

-

-

 
  1. SF SeptiFast, BC blood culture, C Candida, P Pseudomonas, K Klebsiella, E Enterobacter, S Staphylococcus, i.v intravenous
  2. aPathogen in sputum: pathogen detected in sputum during the previous year