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Table 1 Perinatal characteristics of study participants born preterm, by BPD severity

From: Lung function development after preterm birth in relation to severity of Bronchopulmonary dysplasia

 

Mild BPD

Moderate BPD

Severe BPD

All BPD

Non-BPD

P-values

n = 17

n = 7

n = 4

n = 28

n = 23

(All vs Non BPD)

Gestational age at birth, weeks

27 (24–30)

28 (25–30)

28 (25–29)

27 (24–30)

30 (28–31)

<0.001

Birth weight, g

995 (654–1520)

1145 (597–1252)

905 (775–1210)

1003 (597–1520)

1425 (845–2094)

0.001

Male sex

12 (71%)

6 (86%)

2 (50%)

21 (75%)

12 (52%)

0.51

Instillation of surfactant

1 (5.9%)

3 (43%)

2 (50%)

6 (21%)

1 (4.3%)

0.24

Ventilation therapy, days

0 (0–34)

4 (0–38)

23 (0–33)

1 (0–38)

0 (0–5)

0.003

CPAP, days

31 (4–70)

32 (3–55)

38.5 (13–60)

32 (3–70)

4 (0–18)

<0.001

Supplemental O2, days

54 (27–83)

72 (28–96)

141 (105–180)

62 (27–180)

3 (0–26)

<0.001

Maternal smoking during pregnancy

2 (12%)

2 (29%)

4 (100%)

8 (29%)

6 (26%)

0.06

Prenatal corticosteroid therapy

10 (60%)

4 (57%)

2 (50%)

16 (57%)

15 (65%)

0.96

Septicemia

9 (53%)

4 (57%)

3 (75%)

16 (57%)

4 (17%)

0.22

PDA

9 (53%)

5 (71%)

2 (50%)

16 (57%)

7 (30%)

0.36

ROP grade 3–4

5 (29%)

3 (43%)

2 (50%)

10 (36%)

1 (4.3%)

0.007

  1. Abbreviations: BPD Bronchopulmonary dysplasia, CPAP continuous positive airway pressure, PDA patent ductus arteriosus, ROP retinopathy of prematurity
  2. Data are presented as median (range) or numbers (%)