From: Lung function development after preterm birth in relation to severity of Bronchopulmonary dysplasia
Mild BPD | Moderate BPD | Severe BPD | All BPD | Non-BPD | P-values | |
---|---|---|---|---|---|---|
n = 17 | n = 7 | n = 4 | n = 28 | n = 23 | (All vs Non BPD) | |
Gestational age at birth, weeks | 27 (24–30) | 28 (25–30) | 28 (25–29) | 27 (24–30) | 30 (28–31) | <0.001 |
Birth weight, g | 995 (654–1520) | 1145 (597–1252) | 905 (775–1210) | 1003 (597–1520) | 1425 (845–2094) | 0.001 |
Male sex | 12 (71%) | 6 (86%) | 2 (50%) | 21 (75%) | 12 (52%) | 0.51 |
Instillation of surfactant | 1 (5.9%) | 3 (43%) | 2 (50%) | 6 (21%) | 1 (4.3%) | 0.24 |
Ventilation therapy, days | 0 (0–34) | 4 (0–38) | 23 (0–33) | 1 (0–38) | 0 (0–5) | 0.003 |
CPAP, days | 31 (4–70) | 32 (3–55) | 38.5 (13–60) | 32 (3–70) | 4 (0–18) | <0.001 |
Supplemental O2, days | 54 (27–83) | 72 (28–96) | 141 (105–180) | 62 (27–180) | 3 (0–26) | <0.001 |
Maternal smoking during pregnancy | 2 (12%) | 2 (29%) | 4 (100%) | 8 (29%) | 6 (26%) | 0.06 |
Prenatal corticosteroid therapy | 10 (60%) | 4 (57%) | 2 (50%) | 16 (57%) | 15 (65%) | 0.96 |
Septicemia | 9 (53%) | 4 (57%) | 3 (75%) | 16 (57%) | 4 (17%) | 0.22 |
PDA | 9 (53%) | 5 (71%) | 2 (50%) | 16 (57%) | 7 (30%) | 0.36 |
ROP grade 3–4 | 5 (29%) | 3 (43%) | 2 (50%) | 10 (36%) | 1 (4.3%) | 0.007 |