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Table 4 Discriminative performance of DCN-CS in NSCLC and IPF

From: Cathepsin-S degraded decorin are elevated in fibrotic lung disorders – development and biological validation of a new serum biomarker

 

Cut-off value (ng/mL)

Sensitivity

Specificity

AUROC (95% CI)

p-value

NSCLC vs. healthy controls

21.5

90.0

100.0

0.96 (0.90–0.99)

<0.0001

IPF vs. healthy controls

8.9

62.9

82.7

0.77 (0.71–0.83)

<0.0001