Table 2 Patient characteristics
Factor, mean (SD) or n (%) | Treated (N = 828) | Untreated (N = 909) |
|---|---|---|
Mean (SD) age, years | 66.6 (9.3) | 70.1 (11.4)** |
Male | 568 (68.6) | 570 (62.7)** |
MDT evaluation | 687 (83.0) | 520 (57.2)** |
Confirmed IPF | 696 (84.1) | 462 (50.8)** |
IPF severity at diagnosis | ||
Mild | 213 (25.7) | 395 (43.5)** |
Moderate | 530 (64.0) | 367 (40.4)** |
Severe | 85 (10.3) | 147 (16.2)** |
Mean (SD) time from diagnosis to most recent consultation, months | 15.8 (21.8) | 15.9 (22.4) |
Symptomatic at initiation of current treatment | 746 (90.1) | 430 (85.4)a** |
Candidate for lung transplantation | 154 (18.6) | 66 (7.3)** |
Lung comorbidities | 323 (39.0) | 460 (50.6)** |
Emphysema | 187 (22.6) | 299 (32.9)** |
Lung cancer | 20 (2.4) | 46 (5.1)** |
Pulmonary hypertension | 184 (22.2) | 229 (25.2) |
CV comorbidities | 320 (38.6) | 406 (44.7)* |
High risk of coronary artery disease | 131 (15.8) | 153 (16.8) |
Coronary artery disease without history of MI or stroke | 119 (14.4) | 143 (15.7) |
Coronary artery disease with history of MI | 88 (10.6) | 135 (14.9)** |
Other comorbidities | ||
GERD | 262 (31.6) | 257 (28.3) |
Depression | 199 (24.0) | 200 (22.0) |
Obstructive sleep apnea syndrome | 103 (12.4) | 109 (12.0) |
Increased risk of bleedingb | 38 (4.6) | 44 (4.8) |
Other | 111 (13.4) | 149 (16.4) |