Table 1 Patient characteristics and lung function at screening visit

 Sample size (n)

50

27

77

 Sex (male/female)

42/8

15/12

57/20

 Age, years (mean ± SD)

67.2 ± 8.5

64.4 ± 8.2

66.2 ± 8.5

 FEV₁ group: 30–50% (n)

31

7

38

 FEV₁ group: < 30% (n)

19

20

39

 pred. FEV₁, % (mean ± SD)

34.5 ± 11.2

24.9 ± 9.2

31.0 ± 11.4

 LTOT, O₂ L/min (mean ± SD)

2.2 ± 1.7

2.4 ± 1.4

2.2 ± 1.6

 PaO₂, mmHg (mean ± SD)

51.0 ± 6.1

47.0 ± 5.6

49.6 ± 6.2

 PaCO₂, mmHg (mean ± SD)

40.0 ± 4.1

49.1 ± 5.4

43.2 ± 6.3

 SpO₂ (%)

91 ± 2

89 ± 3

91 ± 2