From: Long-term prognosis of chronic cough: a prospective, observational cohort study
Age, years | 59 ± 11 |
Female sex | 51 (75%) |
Body mass index at initial assessment, kg/m2 | 27.6 ± 4.3 |
Atopic subjects | 28 (41%) |
Ex-smokers | 27 (40%) |
Current smokers | 1 (2%) |
Passive smoking | 6 (9%) |
Pet ownership | 24 (35%) |
Home damaged by dampness | 8 (12%) |
Duration of cough at initial assessment, years | 6.0 ± 6.3 |
Presence of an autoimmune disease | 17 (25%) |
with hypothyroidism | 13 |
Presence of chronic rhinitis | 32 (47%) |
with nasal corticosteroids | 21 |
with antihistamines | 9 |
Presence of doctor’s diagnosis of asthma | 34 (50%) |
with inhaled corticosteroids | 27 |
Presence of esophageal reflux disease | 17 (25%) |
with proton pump inhibitors | 6 |
Responsiveness to histamine airway challenge at initial assessment, RDR, %/mg a | 10 ± 5 |
Responsiveness to hypertonic saline cough provocation test at initial assessment, CDR, coughs/Osm/kg a | 4.7 ± 7.1 |
Mean daily mean peak flow variation at initial assessment, percent | 6.1 ± 4.3 |
FEV1 at initial assessment, percent of predicted b | 96 ± 14 |
Improvement in FEV1 after salbutamol at initial assessment, percent | 4.3 ± 4.7 |
Exhaled nitric oxide concentration at initial assessment, ppm | 21 ± 19 |