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Table 5 Laboratory and ultrasonic data in the respiratory failure and extubation success subgroups before and after SBT

From: Different effects of cardiac and diaphragm function assessed by ultrasound on extubation outcomes in difficult-to-wean patients: a cohort study

 

Respiratory failure subgroup

Extubation success subgroup

Variables

RI subgroup

NI subgroup

RI subgroup

NI subgroup

N (cases)

10

19

4

27

Before SBT

 PH

7.44 ± 0.06

7.46 ± 0.06

7.47 ± 0.05

7.46 ± 0.05

 PaCO2 (mmHg)

51.1 ± 15.3

44.2 ± 11.6

38.8 ± 9.5

39.1 ± 4.4

 PaO2/FiO2

311 ± 88

261 ± 77

304 ± 99

278 ± 78

 Lactic acid (mmol/l)

1.2 ± 0.6

1.1 ± 0.7

1.1 ± 0.8

1.1 ± 0.3

 NT-pro-BNP (pg/ml)

8907 ± 10,180

5262 ± 8597

3043 ± 2014

1344 ± 1744

 Pleural effusion

7 (70)

15 (79)

4 (100)

20 (74)

 LVEF (%)

58 ± 16

57 ± 14

58.5 ± 7.9

65.3 ± 8.9

 E (cm/s)

97.0 ± 24.6

90.7 ± 26.4

82.1 ± 28.6

77.6 ± 17.2

 E/Ea (septal)

17.2 ± 11.0

18.7 ± 6.4

12.8 ± 5.9

13.0 ± 3.6

 E/Ea (lateral)

11.7 ± 6.0

13.4 ± 4.6

6.6 ± 3.0

8.7 ± 2.6

 E/Ea (average)

13.5 ± 6.7

15.4 ± 5.1

8.6 ± 3.9

10.3 ± 2.6

 DE (right) (mm)

9.6 ± 4.4

12.1 ± 4.8

6.0 ± 1.4

10.7 ± 4.7

 DE (left) (mm)

10.4 ± 5.1

12.3 ± 6.9

8.3 ± 3.7

11.2 ± 5.6

 DE (average) (mm)

10.0 ± 3.4

12.2 ± 4.9

7.2 ± 2.3

11.0 ± 3.2*

After SBT

 PH

7.43 ± 0.05

7.44 ± 0.06

7.42 ± 0.05

7.47 ± 0.04*

 PaCO2 (mmHg)

51.5 ± 14.2

46.1 ± 10.1

39.3 ± 7.0

38.6 ± 5.4

 PaO2/FiO2

317 ± 107

278 ± 101

307 ± 59

271 ± 81

 Lactic acid (mmol/l)

1.1 ± 0.5

1.1 ± 0.6

1.5 ± 1.0

1.0 ± 0.3

 NT-pro-BNP (pg/ml)

8778 ± 11,082

5329 ± 8654

3631 ± 3273

1138 ± 1517*

 E (cm/s)

99.2 ± 27.3

99.9 ± 23.3

83.5 ± 23.5

85.3 ± 17.8

 E/Ea (septal)

17.8 ± 7.8

19.0 ± 5.8

12.6 ± 5.3

13.5 ± 4.4

 E/Ea (lateral)

13.2 ± 8.0

15.0 ± 7.0

7.2 ± 2.5

9.2 ± 3.0

 E/Ea (average)

14.6 ± 7.0

16.4 ± 5.9

9.1 ± 3.4

10.8 ± 3.1

 DE (right) (mm)

8.9 ± 4.6

16.2 ± 5.1*

8.2 ± 2.4

11.5 ± 4.5

 DE (left) (mm)

10.7 ± 5.3

15.5 ± 6.4

9.6 ± 2.4

13.5 ± 5.5

 DE (average) (mm)

9.8 ± 3.6

15.8 ± 5.1*

8.9 ± 1.9

12.5 ± 3.4*

  1. Data are in median ± SD or median (IQR) or n (%). DE diaphragmatic excursion, E mitral Doppler early peak diastolic velocity, E/Ea the ratio of mitral Doppler inflow velocity to annular tissue Doppler wave velocity, LVEF left ventricular ejection fraction, NI non-intubation, NT-pro-BNP N-terminal-pro-B-type natriuretic peptide, PaCO 2 arterial carbon dioxide tension, PaO 2 /FiO 2 the ratio of arterial oxygen tension to fraction of inspired oxygen, RI re-intubation, SBT spontaneous breathing trial. *p < 0.05