Table 1 Clinical summary of all studies
Interleukins | Author | Country(incidence) | Year | Cut-off (pg/ml) | Index test | Design |
|---|---|---|---|---|---|---|
IL-27 | Wu et al. [16] | China (high) | 2013 | 900.8 | ELISA | P |
Liu et al. [42] | China (high) | 2015 | 1012 | ELISA | R | |
Luo et al. [27] | China (high) | 2015 | 353.47 | ELISA | R | |
Skouras et al. [46] | Greece (low) | 2015 | 391 | ELISA | NA | |
Sun et al. [29] | China (high) | 2014 | 838 | ELISA | R | |
Valdes et al. [31] | Spain (low) | 2014 | 550 | ELISA | P | |
Yang et al. [50] | China (high) | 2012 | 1007 | ELISA | P | |
Niu et al. [38] | China (high) | 2012 | 846 | ELISA | R | |
IL-18 | Chen et al. [17] | China (high) | 2011 | 843.7 | ELISA | R |
Dai et al. [18] | China (high) | 2015 | 503.58 | ELISA | R | |
Ding et al. [19] | China (high) | 2008 | 640 | ELISA | R | |
Hu et al. [21] | China (high) | 2009 | 365 | ELISA | R | |
Jiang et al. [22] | China (high) | 2009 | 503.88 | ELISA | R | |
Klimiuk et al. [39] | Poland (low) | 2014 | 327.7 | ELISA | P | |
Liu et al. [43] | China (high) | 2015 | 438.86 | ELISA | R | |
Okamoto et al. [44] | Japan (low) | 2005 | 992.7 | ELISA | NA | |
Wang et al. [47] | China (high) | 2008 | 358 | ELISA | R | |
Wu et al. [33] | China (high) | 2006 | 150 | ELISA | R | |
Xiong et al. [34] | China (high) | 2007 | 358 | ELISA | R | |
Yu et al. [51] | China (high) | 2003 | 150 | ELISA | NA | |
IL-6 | Kiropoulos et al. [24] | Greece (low) | 2007 | 17,215 | ELISA | P |
Wang et al. [32] | China (high) | 2005 | 1950 | ELISA | R | |
Wong et al. [48] | China (high) | 2003 | 4000 | ELISA | P | |
Wu et al. [49] | China (high) | 2005 | 550 | ELISA | R | |
Zan et al. [35] | China (high) | 2014 | 277 | RIA | NA | |
Yang et al. [37] | China (high) | 2006 | 220 | RIA | R | |
IL-33 | Lee et al. [26] | Korea (low) | 2013 | 10 | ELISA | R |
Li et al. [40] | China (high) | 2015 | 68.3 | ELISA | R | |
Liu et al. [42] | China (high) | 2015 | 19.31 | ELISA | R | |
Xuan et al. [36] | China (high) | 2014 | 19.86 | ELISA | R | |
IL-12 | Chen et al. [17] | China (high) | 2011 | 785.6 | ELISA | R |
Gu et al. [20] | China (high) | 2002 | 300 | ELISA | NA | |
Jiang et al. [23] | China (high) | 2010 | 87.41 | ELISA | R | |
Okamoto et al. [44] | Japan (low) | 2005 | 129 | ELISA | NA | |
Tian et al. [28] | China (high) | 2004 | 73.5 | ELISA | R | |
Zhou et al. [53] | China (high) | 2012 | 90 | ELISA | R | |
IL-2 | Liu et al. [43] | China (high) | 2015 | 67.17 | ELISA | R |
Liu et al. [42] | China (high) | 2015 | 99.08 | ELISA | R | |
Ren et al. [25] | China (high) | 2014 | 41.91 | ELISA | R | |
Wu et al. [49] | China (high) | 2005 | 250 | ELISA | R | |
Zhang et al. [52] | China (high) | 1998 | 400 | RIA | R | |
IL-12p40 | Fernández et al. [41] | Venezuela (low) | 2011 | 89 | ELISA | NA |
Klimiuk et al. [39] | Poland (low) | 2014 | 296 | ELISA | P | |
Tural Önür et al. [45] | Turkey (low) | 2015 | 210 | ELISA | NA | |
Valdes et al. [30] | Spain (low) | 2009 | 550 | ELISA | P | |
IL-8 | Yamada et al. [57] | Japan (low) | 2001 | 228 | ELISA | R |
Yang et al. [56] | China (high) | 2001 | 1000 | ELISA | R | |
IL-10 | Wu et al. [49] | China (high) | 2005 | 50 | ELISA | R |
IL-22 | Jin et al. [58] | China (high) | 2011 | 49 | ELISA | R |
Yuan et al. [55] | China (high) | 2014 | 186.6 | ELISA | R | |
IL-23 | Klimiuk et al. [39] | Poland (low) | 2014 | 0.7 | ELISA | P |
IL-31 | Gao et al. [54] | China (high) | 2015 | 67.5 | ELISA | R |