Table 1 Clinical characteristics of 244 Mycobacterium avium complex lung disease patients with and without chronic Pseudomonas aeruginosa infection
Characteristic | All patients (n = 244) | With chronic infection (n = 19) | Without chronic infection (n = 225) | P value |
|---|---|---|---|---|
Age, years | 68 (62–75) | 74 (67–76) | 67 (61–75) | 0.055 |
Sex, female | 196 (80) | 14 (74) | 182 (81) | 0.546 |
Disease duration, years | 5.7 (2.3–9.7) | 5.3 (2.3–10.3) | 5.8 (2.3–9.6) | 0.622 |
Body mass index, kg/m2 | 19.5 (17.5–21.3) | 18.8 (17.3–21.2) | 19.6 (17.5–21.3) | 0.515 |
Smoking status | 1.000 | |||
Never | 220 (90) | 17 (89) | 202 (90) | |
Former | 25 (10) | 2 (11) | 23 (10) | |
Current | 0 (0) | 0 (0) | 0 (0) | |
Charlson Comorbidity Index | 0 (0–1) | 1 (1–1) | 0 (0–1) | 0.048 |
Underlying pulmonary disease | ||||
History of pulmonary TB | 23 (9) | 4 (21) | 19 (8) | 0.089 |
Asthma | 8 (3) | 1 (1) | 7 (3) | 0.482 |
COPD | 2 (1) | 0 (0) | 2 (1) | 1.000 |
Lung cancer | 3 (1) | 1 (1) | 2 (1) | 1.000 |
Interstitial lung disease | 1 (0.4) | 0 (0) | 1 (0.4) | 1.000 |
Treatment status | 0.452 | |||
Never | 116 (48) | 10 (53) | 106 (47) | |
Previous | 40 (16) | 1 (5) | 39 (17) | |
Current | 88 (36) | 8 (42) | 80 (36) | |
Bacterial statusa | ||||
Positive smear | 83 (34) | 3 (15) | 80 (36) | 0.083 |
Positive culture | 138 (57) | 7 (37) | 131 (59) | 0.090 |